Protocol summary

Study aim
Determining the effect of laughter therapy on anxiety in patients with gastrointestinal cancers undergoing chemotherapy
Design
The present study is an experimental study of pre-test-post-test with a control group and in a single-blind manner. In this clinical trial study, 60 patients undergoing chemotherapy and inclusion criteria were selected and divided into two groups of intervention and control by minimization technique.
Settings and conduct
The study units included 60 patients undergoing chemotherapy in the Imam Khomeini Hospital of Ardabil. 30 minutes before the intervention, the intensity of the patient's anxiety was assessed in both groups, and the intervention group was treated with a funny clip or movie for 30 minutes once a day as a group and in one of the ward rooms, and 30 minutes later, the severity of anxiety assessed again. In the control group, the severity of anxiety is also assessed, only the patient will receive routine intervention instead of intervention.
Participants/Inclusion and exclusion criteria
Be 18-70 years old; have gastrointestinal cancer and undergo at least one chemotherapy course and be hospitalized for at least three days; have no hearing or visual impairment, mental disorder, recent surgery, glaucoma, transmissible respiratory disease, and heart disease. Be a native of the province. Exclusion criteria: unwillingness to participate in the study; patient transfer to home; patient's death; Absence of the patient in meetings even once; change of medication type or increase or decrease of anxiolytic drug dose during the intervention.
Intervention groups
Patients in the intervention group participate in laughter therapy sessions once a day for half an hour and three consecutive days. Meetings will be held with comedy videos and comic clips. Patients in the control group receive routine care.
Main outcome variables
anxiety

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20200819048458N1
Registration date: 2020-10-07, 1399/07/16
Registration timing: retrospective

Last update: 2020-10-07, 1399/07/16
Update count: 0
Registration date
2020-10-07, 1399/07/16
Registrant information
Name
Mehdi Ajri-khameslou
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 45 3372 6085
Email address
ajri@sbmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-08-23, 1398/06/01
Expected recruitment end date
2019-12-22, 1398/10/01
Actual recruitment start date
2019-09-23, 1398/07/01
Actual recruitment end date
2020-01-21, 1398/11/01
Trial completion date
2020-01-21, 1398/11/01
Scientific title
The effect of laughter therapy on anxiety in patients with gastrointestinal cancers undergoing chemotherapy
Public title
The effect of laughter therapy in patients with gastrointestinal cancers
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Willingness to participate in the study Having a gastrointestinal cancers Existence of anxiety based on visual analog scale Do not have audible and visual problems Do not use radiotherapy along with chemotherapy
Exclusion criteria:
Discharge from the hospital Death of the patient Absence of the patient in laughter therapy sessions even once increase or decrease the dose of anxiety medication during the intervention
Age
From 18 years old to 70 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 60
Actual sample size reached: 60
Randomization (investigator's opinion)
Randomized
Randomization description
The study units were divided into intervention and control groups with Minimazation technique on 3 variables: age (in the range of 18-35, 36-32 and 53-70), sex (female or male) and disease severity (stageII, stageIII and stageIV) and with Using the Minimization ۥ Taves formula.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Ardabil University of Medical Sciences
Street address
Vice Chancellor for Research and Technology, Ardebil University of Medical Sciences, North side, University square, University street
City
Ardabil
Province
Ardabil
Postal code
5618985991
Approval date
2019-08-23, 1398/06/01
Ethics committee reference number
IR.ARUMS.REC.1398.318

Health conditions studied

1

Description of health condition studied
Malignant neoplasms of digestive organs
ICD-10 code
C15-C26
ICD-10 code description
Malignant neoplasms of digestive organs

Primary outcomes

1

Description
Anxiety in patients undergoing chemotherapy
Timepoint
30 min before and 30 min after laughter therapy in both groups and daily for three days.
Method of measurement
spilberger anxiety questionnaire

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: In the intervention group, laughter therapy performed with comedy videos and humorous clips for 30 minutes once a day for 3 consecutive days
Category
Behavior

2

Description
Control group: patients received routine care.
Category
Behavior

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam Khomeini Hospital Ardabil
Full name of responsible person
Dr farzaneh
Street address
Imam Khomeini Hospital Ardabil, saheli street, ardabil, iran
City
Ardabil
Province
Ardabil
Postal code
5618953141
Phone
+98 45 3325 1401
Email
Emamhe@arums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ardabil University of Medical Sciences
Full name of responsible person
Dr.shahab bohlooli
Street address
Ardabil University of Medical Sciences Administrative Complex, End of University Street
City
Ardabil
Province
Ardabil
Postal code
۵۶۱۸۹-۸۵۹۹۱
Phone
+98 45 3353 4715
Email
ravabet@arums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ardabil University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Ardabil University of Medical Sciences
Full name of responsible person
Mehdi Ajri-khameslou
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Ardabil School of Nursing and Midwifery, Between Hafez and Saadi crossroads, Martyrs Highway
City
Ardabil
Province
Ardabil
Postal code
5615754136
Phone
+98 45 3372 6085
Fax
+98 45 3372 8004
Email
ajri.mehdi@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ardabil University of Medical Sciences
Full name of responsible person
Mehdi Ajri-khameslou
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Ardabil School of Nursing and Midwifery, Between Hafez and Saadi crossroads, Martyrs Highway
City
Ardabil
Province
Ardabil
Postal code
5615754136
Phone
+98 45 3372 6085
Email
ajri.mehdi@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Ardabil University of Medical Sciences
Full name of responsible person
Mehdi Ajri-khameslou
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Ardabil School of Nursing and Midwifery, Between Hafez and Saadi crossroads, Martyrs Highway
City
Ardabil
Province
Ardabil
Postal code
5615754136
Phone
+98 45 3372 6085
Email
ajri.mehdi@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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