Protocol summary

Summary
The objective of this study was to compare open surgery with TURP in BPH cases. 200 patients with moderate size BPH who were candidates of surgery were randomly assigned to undergo open prostatectomy or TURP. Transrectal sonography, lab tests, International Prostate Symptom Score (IPSS) and uroflumetry were done for all patients at baseline and follow-up visits. Patients were visited one and 6 month after surgery and uroflumetry and systoscopy were done for them. The results were compared between study groups

General information

Acronym
IRCT registration information
IRCT registration number: IRCT138803181267N13
Registration date: 2009-08-24, 1388/06/02
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2009-08-24, 1388/06/02
Registrant information
Name
Mojgan Borgheie
Name of organization / entity
Urology and Nephrology Research Center (UNRC), Shahid Beheshti University of Mediacal Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 2256 7222
Email address
research@unrc.ir
Recruitment status
Recruitment complete
Funding source
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.R. Iran
Expected recruitment start date
2005-11-22, 1384/09/01
Expected recruitment end date
2007-11-22, 1386/09/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of outcome and complications of open prostatectomy and TURP in treatment of medium- size hypertrophic prostate.
Public title
Comparison of outcome and complications of open prostatectomy and TURP in treatment of medium- size hypertrophic prostate.
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: Prostate larger than normal and have one of these conditions:1 acute urinary retention more than one time 2.recurrent infection 3. recurrent hematuria 3. azotemia 4. dissatisfaction after treatment 5. absence of bladder stone or diverticule Exclusion Criteria: 1. bladder stone larger than 2 cm 2. weight of prostate more than 75 grams and less than 30 grams 3. resectable bladder diverticule 4.anclusis and orthopedic problems 5. previous urethra problems 6. hernia 7. suspicious for PSA>4 or suspicious nodule in touch 8. DRE previous prostatectomy 9. others pathology results than BPH
Age
No age limit
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 200
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University
Street address
UNRC, No.101, 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Approval date
2005-10-01, 1384/07/09
Ethics committee reference number
58

Health conditions studied

1

Description of health condition studied
BPH
ICD-10 code
N40
ICD-10 code description
Hyperplasia of prostate

Primary outcomes

1

Description
complication of surgery
Timepoint
during surgery ,1 and 6 month after surgery
Method of measurement
observation and phisical exam

2

Description
urrinary symptom
Timepoint
before surgery ,1 and 6 month after surgery
Method of measurement
International Prostate Symptom Score (IPSS)

Secondary outcomes

1

Description
Prostate situation
Timepoint
After surgery
Method of measurement
systoscopy

Intervention groups

1

Description
TURP surgery
Category
Treatment - Surgery

2

Description
open surgery
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Labafi Nejad Hospital
Full name of responsible person
Street address
Labafi Nejad Hospital.,9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
shabnam golshan
Street address
UNRC, No.101, 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Dr Ali Tabibi
Position
Associate Professor
Other areas of specialty/work
Street address
UNRC, No.101,9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
Research @unrc.ir
Web page address
www.unrc.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Dr Naser Simforoush
Position
professor
Other areas of specialty/work
Street address
UNRC, No.101, Boostan 9th St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
Tabibiali@yahoo.com
Web page address
www.unrc.ir

Person responsible for updating data

Contact
Name of organization / entity
Urology and Nephrology Research Center
Full name of responsible person
Dr Mozhgan Borgheie
Position
General Physician
Other areas of specialty/work
Street address
UNRC, No.101, 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
borgheie@unrc.ir
Web page address
www.unrc.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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