The effect of supplementation with Ganoderma lucidum on anthropometric indices,chemical biomarkers and blood pressure of people with overweight

the effect of Ganoderma lucidum supplementation on anthropometric indices, chemical biomarkers and blood pressure in overweight people

A clinical trial with a control group, with a parallel, double-blind, randomized, phase 3 group on 72 patients, used the rand function of Excel software for randomization.

The study was performed in Salahuddin Ayoubi Hospital in Baneh. They were randomly divided into two groups of intervention and control. Patients who were eligible for the study were randomly divided into two groups of placebo and medicine. Whether the drug was a placebo or an intervention was unknown but the researcher was aware. Patients and drugs were coded by the researcher.

Inclusion criteria:Age 60 to 18 years, personal satisfaction,Body mass index 25 to 29.9, no underlying diseases interfering with weight loss and drug use, use of any type of weight loss and fat or blood pressure monitor and blood sugar control, non-pregnancy and lactation.Exclusion criteria:taking Weight loss supplements,following a diet to lose weight,diseases associated with metabolic changes such as thyroid disease,taking drug that inhibit platelet aggregation (such as aspirin or warfarin) ,unavailability of any reason

Intervention group: Patients received 3 capsules of Ganoderma daily, each capsule containing 220 mg of complete powder of Ganoderma lucidum and 30 mg of pure aqueous extract of Ganoderma lucidum for 6 weeks. Control group: Patients received 3 capsules daily, each containing 250 mg of wheat flour for 6 weeks.

Body mass index(BMI) , weight, waist circumference, hip circumference, waist to hip ratio, arm circumference, total cholesterol concentration,Low density lipoprotein(LDL),High density lipoprotein(HDL) , triglyceride, blood sugar, blood pressure,Physical activity

Sampling was done by simple random sampling so that 72 people were selected using a random table of numbers and randomly assigned by random numbers by random numbers in Exel software were divided into two groups of intervention and control (default: numbers Pairs in Ganoderma supplement group = intervention group and individual numbers in group of capsules filled with wheat flour = in control group)

All patients who were eligible for the study were randomly divided into placebo and drug groups. Patients and laboratory staff and physicians were unaware of the intervention drug or placebo. But the researcher knew whether the intervention was drug or placebo. And the drugs were coded by the researcher. The dressing was such that the placebo was the same shape, color, and taste of the drug. That is, the drug and the placebo were both similar in appearance. But the placebo capsules contained wheat flour.