Comparison of Tramadol and Lidocaine and placebo jelly in 150 patients candidate for laparoscopic cholecystectomy from bucking, coughing and sore throat after endotracheal extubation.

This study will be done with aim to compare the effects of lidocaine topical gel with tramadol gel on coughing, straining and throat caused by the endotracheal tube.Inclusion criteria are: age between 20 and 60 years; patient informed consent;patients admitted for cholecystectomy laparoscopic surgery; ASA class 1,2; mallampati 1 or 2 and Exclusion criteria are: history of smoking or drug abuse;a history of catching a cold in the last two weeks; patients with COPD, and convulsions. This is a double blind experimental study. The study population consisted of patients undergoing laparoscopic cholecystectomy that referring to Imam Reza Hospital of Kermanshah and by random permutation blocks150 persons will selected and will divided in five equal groups. All patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesia. Isoflurane gas is used to maintain anesthesia.In the first group endotracheal tube cuff with tramadol gel 2.5%, in the second group with tramadol gel 5%, the third group with lidocaine gel 2% and in the fourth group is smeared with 1cc 0f each of pure gel.In the control group do not use the gel and intubation performed as usual.The patients for the occurrence of straining and cough and laryngospasm and bronchospasm will control and data will recorded in a special form. Then all patients at a distance of one, six and twelve hours after the operation will checked in severity of throat pain using the VAS and information will recorded.

Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences