Protocol summary

Study aim
The effect of perineuropathy and posterior anterior repair (APR) on body image, sexual function and quality of life in postoperative women
Design
A clinical trial without a control and non-blind group in which the study and randomization phase does not apply in this study on 119 female patients with rectocele, cystocele and uterine prolapse who are candidates for perineural surgery and posterior anterior repair (APR)
Settings and conduct
The researcher refers to the mentioned hospitals. While introducing himself to the clients he talks about the study and its goals and explains the ethical considerations. The informed consent form is obtained from the subjects. Then three questionnaires of women's sexual satisfaction body image and quality of life; It is explained to the patients and in case of complete and informed consent it is delivered to them and collected after completion. Patients undergo perineurography and anterior-posterior repair (APR). Six months after the above operation, three questionnaires are completed again.
Participants/Inclusion and exclusion criteria
Inclusion criteria: women with rectocele, cystocele and uterine prolapse candidate for perineuropathy and posterior anterior repair (APR) surgery; consent to enter the study. Exclusion criteria: lack of access to the subject for follow-up; do not tend to continue participation in the study
Intervention groups
Women with rectocele, cystocele and uterine prolapse, etc., who are candidates for perineuropathy and posterior anterior repair (APR) surgery; Are selected.They undergo perineurectomy and posterior anterior repair (APR).
Main outcome variables
Body image, sexual function

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20160521027998N9
Registration date: 2021-04-15, 1400/01/26
Registration timing: registered_while_recruiting

Last update: 2021-04-15, 1400/01/26
Update count: 0
Registration date
2021-04-15, 1400/01/26
Registrant information
Name
Maryam Hajihashemi
Name of organization / entity
Isfahan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 31 3776 6578
Email address
m_hajihashemy@med.mui.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-02-19, 1399/12/01
Expected recruitment end date
2022-02-20, 1400/12/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of perineuropathy and posterior anterior repair (APR) on body image, sexual function and quality of life in postoperative women
Public title
The effect of perineuropathy and posterior anterior repair (APR) in postoperative patients
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Women with rectocele, cystocele and uterine prolapse candidate for perineural surgery and posterior anterior repair (APR) Satisfaction to enter the research
Exclusion criteria:
Exclusion of the subject from the study Lack of access to the subject to follow up
Age
From 25 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 119
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Isfahan University of Medical Sciences
Street address
Isfahan University of Medical Sciences, Azadi Square
City
Esfahan
Province
Isfehan
Postal code
8184853541
Approval date
2020-10-07, 1399/07/16
Ethics committee reference number
IR.MUI.MED.REC.1399.583

Health conditions studied

1

Description of health condition studied
Rectocell
ICD-10 code
N81.6
ICD-10 code description
Rectocele

2

Description of health condition studied
Cystocell
ICD-10 code
N81.1
ICD-10 code description
Cystocele

3

Description of health condition studied
uterine prolapse
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Body image
Timepoint
Before surgery and six months after surgery
Method of measurement
Questionnaire MBSRQ

2

Description
Sexual function
Timepoint
Before surgery and six months after surgery
Method of measurement
Questionnaire FSFI

Secondary outcomes

1

Description
Quality of Life
Timepoint
Before surgery and six months after surgery
Method of measurement
questionnaire sf-36

Intervention groups

1

Description
Intervention group: This study is performed among patients referred to Isfahan women's centers and hospitals. Women who have been diagnosed with rectocele, cystocele and uterine prolapse, etc., and are candidates for perineuropathy and posterior anterior repair (APR) surgery; Are selected. Due to the immorality of depriving patients of treatment, it is not possible to select a control group. Sampling is done by available census. The researcher refers to the mentioned hospitals. While introducing himself to the clients, he talks about the study and its goals and explains the ethical considerations. The informed consent form is obtained from the subjects. Then three questionnaires of women's sexual satisfaction, body image and quality of life; It is explained to the patients and in case of complete and informed consent, it is delivered to them and collected after completion. Patients undergo perineurography and posterior anterior repair (APR). Six months after the above operation, three questionnaires of women's sexual satisfaction, body image and quality of life, distribution, completion and collection are again.
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Beheshti hospital
Full name of responsible person
Maryam Hajhashemi
Street address
Beheshti hospital, Motahhari street
City
Esfahan
Province
Isfehan
Postal code
8184853542
Phone
+98 31 3236 3500
Email
hajhashemy73@yahoo.com

2

Recruitment center
Name of recruitment center
Alzahra hospital
Full name of responsible person
Maryam Hajhashemi
Street address
Al-Zahra Hospital, Shahid Keshvari Highway, Sofeh Boulevard
City
Esfahan
Province
Isfehan
Postal code
8174675731
Phone
+98 21 3620 2020
Email
hajhashemy73@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Dr. Shaghayegh Haghjoi Javanmard
Street address
Vice Chancellor for Research and Technology, Isfahan University of Medical Sciences, Hezar Jerib St.
City
Esfahan
Province
Isfehan
Postal code
7346181746
Phone
+98 31 3668 8138
Email
hajhashemy73@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Esfahan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Maryam Haj Hashemi
Position
Assistant professor
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Beheshti hospital, Motahhari street
City
Isfahan
Province
Isfehan
Postal code
8184853542
Phone
+98 31 3236 7005
Email
hajhashemy73@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Maryam Haj Hashemi
Position
Assistant Professor
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Beheshti hospital, Motahhari street
City
Esfahan
Province
Isfehan
Postal code
8184853542
Phone
+98 31 3236 3500
Email
hajhashemy73@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Maryam Haj Hashemi
Position
Assistant professor
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Beheshti hospital, Motahhari street
City
Esfahan
Province
Isfehan
Postal code
8184853542
Phone
+98 31 3236 3500
Email
hajhashemy73@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
All data can be shared
When the data will become available and for how long
After publishing the article
To whom data/document is available
Scientific and academic researchersا
Under which criteria data/document could be used
Use research documents to benefit from experiences
From where data/document is obtainable
Executor of the project, Maryam Haj Hashemi, hajhashemy73@yahoo.com
What processes are involved for a request to access data/document
After viewing the request, the documents will be sent.
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