First, the research units are selected according to the estimated number of available patients admitted to intensive care units according to the inclusion criteria and in a purposful method. Then, using the quadruple block method, they are randomly assigned to two groups of two touch therapy groups (one group by the patient's own hand with help and the other by the nurse, 24 people in each group). In this way, for the group to be touched by the patient's own hand) with the help of the letter A and for the group to be touched by the nurse's hand, the letter B is considered. Possible modes in the four blocks of six modes include AABB, BBAA, ABAB, BABA, ABBA, BAAB, each mode is written on a card and the cards are assigned the number one to six. Then, using a dice, one of the six possible modes is selected and based on that, the selected patients are assigned to two relevant groups. This process continues until the sample size is completed.