Protocol summary

Study aim
The effect of High-intensity interval circuit functional training on Insulin resistance, hemoglobin A1c, body fat percent, and weight loss in diabetes type 2 need to be scrutinized in more detail.
Design
The clinical trial will be conducted on women with type 2 diabetes ranging from 45 to 55 years old. The participants will be randomised into intervention groups and a parallel control group by using "flip the coin" method.
Settings and conduct
pre and post-intervention anthropometric data and blood samples will be collected. The intervention program will last for 10 weeks and 3 sessions per week. Each session includes about 10 minutes of warm-up, about 25 to 30 minutes of main workout, and 5 to 10 minutes of cool down.
Participants/Inclusion and exclusion criteria
in this study, working women with type 2 diabetes aging from 45 to 55 will take part. people with fasting blood sugar over 120, with a sedentary lifestyle, and without any chronic disease history will meet the inclusion criteria.
Intervention groups
The program for the intervention group will be High-intensity interval circuit functional training that will be held for 10 weeks and 3 sessions per week and include bodyweight exercises. The control group will not receive any intervention.
Main outcome variables
insulin resistance and hemoglobin a1c ؛

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20160103025828N1
Registration date: 2021-05-31, 1400/03/10
Registration timing: registered_while_recruiting

Last update: 2021-05-31, 1400/03/10
Update count: 0
Registration date
2021-05-31, 1400/03/10
Registrant information
Name
Rahman Soori
Name of organization / entity
University of Tehran
Country
Iran (Islamic Republic of)
Phone
+98 21 6111 8844
Email address
soori@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-05-22, 1400/03/01
Expected recruitment end date
2021-06-22, 1400/04/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The Effect of 10 Weeks High‐Intensity Interval Functional Circuit Training on Insulin Resistance and HbA1C in type 2 diabetes women
Public title
Effect of HIIT in type 2 diabetes
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Fasting blood sugar should be over 120 Being a non-athlete diabetic women that are overweight diabetic women that are non-smoker diabetic women that do not drink alcohol
Exclusion criteria:
diabetic women that are suffering from cardiovascular disease diabetic women that are suffering from orthopedic problems diabetic women that are suffering from liver problems diabetic women that are suffering from nouropatic problems
Age
From 45 years old to 55 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 12
Randomization (investigator's opinion)
Randomized
Randomization description
30 women with type 2 diabetes will take part in this study. Their age will range from 45 to 55 years old. This selection was based on a randomized convenience sampling procedure because of the ease of their volunteering, convenient accessibility. All the participants will get familiar with the process. their anthropometric data and blood samples will be collected. The qualified participants will be assigned into two groups randomly by using "flip the coin" method.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
ethics committee of Tehran University of Medical Sciences
Street address
Faculty of Physical Education and Sport Sciences, University of Tehran, North Kargar Ave., Tehran, Iran
City
Tehran
Province
Tehran
Postal code
۱۴۱۵۵۶۶۱۹
Approval date
2021-02-23, 1399/12/05
Ethics committee reference number
IR.TUMS.FNM.REC.1400.001

Health conditions studied

1

Description of health condition studied
diabetes type 2
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Hba1c in women with type 2 diabetes
Timepoint
Measuring Hba1c 24 hours before intervention and 48 to 72 hours after intervention.
Method of measurement
Hba1c blood test

2

Description
Insulin resistance in women with type 2 diabetes
Timepoint
Measuring insulin resistance 24 hours before intervention and 48 to 72 hours after intervention
Method of measurement
measuring insulin resistance by blood test

Secondary outcomes

1

Description
Body fat percent
Timepoint
Measuring body fat percent pre - and post-intervention
Method of measurement
using body composition analyzer scale and caliper

2

Description
Vo2max
Timepoint
pre- and post intervention
Method of measurement
Rockport test

Intervention groups

1

Description
Intervention group: 15 women with diabetes type 2 will be allocated to circuit HIIT group. circuit HIIT will be conducted 3 sessions per week and includes high intensity interval body weight functional movements such as push up, squat, lunge, plank, etc.
Category
Treatment - Other

2

Description
Control group: 15 women with diabetes type 2 will be allocated to control group. This group will not receive any intervention.
Category
Other

Recruitment centers

1

Recruitment center
Name of recruitment center
diabetes and metabolic syndrome clinic
Full name of responsible person
کاملیا رامبد
Street address
No 10, Jalale Al Ahmad St., Next to Dr. Shariati Hospital Complex, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1411713137
Phone
+98 21 8863 1298
Email
emrc@tums.ac.ir

2

Recruitment center
Name of recruitment center
Taban health diabetes clinic
Full name of responsible person
Dr Saeed Kalbasi
Street address
No. 100, Derakhti Ave., Dadman Blvd., Shahrak-e-Qarb, Tehran, IRAN
City
Tehran
Province
Tehran
Postal code
۱۵۹۵۷۶۵۱۲۱
Phone
+98 21 4433 2233
Email
saeid_kalbasi@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Mohamadali Sahraeiyan
Street address
No 1, Enayat alley, Poorsina street, 16 Azar ave., Keshavarz blvd., Tehran
City
Tehran
Province
Tehran
Postal code
۱۴۱۷۶۳۵۴۷۱
Phone
+98 21 8163 3639
Fax
Email
Research@tums.ac.ir
Web page address
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
University of Tehran
Full name of responsible person
Rahman soori
Position
professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
tehran
Province
Tehran
Postal code
۱۴۱۵۵۶۶۱۹
Phone
+98 21 6111 8844
Email
soori@ut.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
University of Tehran
Full name of responsible person
rahman soori
Position
professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
tehran
Province
Tehran
Postal code
۱۴۱۵۵۶۶۱۹
Phone
+98 21 6111 8844
Email
soori@ut.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
University of tehran
Full name of responsible person
Soudabeh Nazari Shoul
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiology
Street address
No 34, Ebadi street, Valiasr ave., Tehran
City
Tehran
Province
Tehran
Postal code
1595765121
Phone
+98 21 4611 2415
Email
soodi_nzsh@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
For more meticulous comparison Blood test results and anthropometric data will be shared anonymously.
When the data will become available and for how long
Data will be accessible 6 mounts after paper publication.
To whom data/document is available
ًesearcher and students focusing on type 2 diabates and exercise training
Under which criteria data/document could be used
For comparing with other studies and using in review articles.
From where data/document is obtainable
Corresponding Author Dr. Rahman Soori soori@ut.ac.ir
What processes are involved for a request to access data/document
Researcher can send an email to the corresponding author and ask for documents. Results will be sent in the next 2 weeks.
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