Protocol summary

Study aim
Comparison of median and Para median methods in the incidence of PDPH in patients undergoing Orthopedic Lower Limb Surgery
Design
This study will be a double-blind randomized clinical trial with Parallel groups on 60 patients referred to Peymaniyeh Hospital in Jahrom who are undergoing orthopedic lower limb surgery. Patients participating in the study will be divided into two groups by tossing coins.
Settings and conduct
Patients referred to Peymaniyeh Hospital in Jahrom who will undergo orthopedic surgery of the lower extremities will be included in the study. Patients participating in the study will be divided into two groups, Madin and Paramedin, by tossing coins. The study participant, researcher, and data collector will be unaware of the type of drug being used.
Participants/Inclusion and exclusion criteria
Inclusion criteria: All patients referred to Peymaniyeh Hospital in Jahrom who underwent lower limb orthopedic surgery and expressed their consent to participate in the study. Non-entry conditions: includes patients who do not have hemodynamic stability and suffer from acute and chronic pain.
Intervention groups
Intervention group 1: Spinal anesthesia in the sitting position of the arachnoid will be performed using a crowford needle with a high gauge 'number' 25 by the median method. Intervention group 2: Spinal anesthesia will be performed using a crowford needle with high gauge 'number' 25 by paramedic method.
Main outcome variables
Headache

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20210415050976N3
Registration date: 2021-06-07, 1400/03/17
Registration timing: prospective

Last update: 2021-06-07, 1400/03/17
Update count: 0
Registration date
2021-06-07, 1400/03/17
Registrant information
Name
navid kalani
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 71 5433 6085
Email address
k.navid@juma.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-07-01, 1400/04/10
Expected recruitment end date
2021-11-01, 1400/08/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of median and Para median methods in the incidence of Post-Dural-puncture headache in patients undergoing Orthopedic Lower Limb Surgery by spinal anesthesia
Public title
Comparison of median and Para median methods in the incidence of Post-Dural-puncture headache in patients undergoing Orthopedic Lower Limb Surgery by spinal anesthesia
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
People who will be operated with spinal anesthesia. Hemodynamic stability
Exclusion criteria:
Chronic pain and cancer Anxiety and mental illness Infection at the site of needle entry Coagulation disorders
Age
From 20 years old to 80 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Investigator
  • Outcome assessor
Sample size
Target sample size: 60
Randomization (investigator's opinion)
Randomized
Randomization description
Patients participating in the present study will be divided into two groups, Median and Paramedian, by tossing coins.
Blinding (investigator's opinion)
Double blinded
Blinding description
For blinding in the present study, the double-blind method is used so that the participant in the study, the researcher and the data collector are not aware of the spinal anesthesia method used.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Jahrom University of Medical Sciences
Street address
Jahrom, Shahid Motahari Boulevard, Jahrom University of Medical Sciences, Vice Chancellor for Research
City
Jahrom
Province
Fars
Postal code
7167758256
Approval date
2020-02-26, 1398/12/07
Ethics committee reference number
IR.JUMS.REC.1398.102

Health conditions studied

1

Description of health condition studied
Orthopedic patients
ICD-10 code
M96.6
ICD-10 code description
Fracture of bone following insertion of orthopedic implant, joint prosthesis, or bone plate

Primary outcomes

1

Description
Headache
Timepoint
Up to 7 days after surgery
Method of measurement
Post-Dural-puncture headache criteria

Secondary outcomes

1

Description
Vital signs
Timepoint
Before spinal anesthesia, after spinal anesthesia and at 5, 15 and 30, 45, 60 and 90 minutes during surgery and in recovery
Method of measurement
Monitoring device

Intervention groups

1

Description
Intervention group 1: Spinal anesthesia in sitting position and in L3-L4 space after washing the place with betadine and alcohol and topical injection of 1 ml of 2% lidocaine and then injection of anesthetic (bupivacaine. 5% CC 12.5 mg) in 5 seconds in space The subarachnoid will be performed us
Category
Treatment - Other

2

Description
Intervention group 2: Spinal anesthesia in sitting position and in L3-L4 space after washing the place with betadine and alcohol and topical injection of 1 ml of 2% lidocaine and then injection of anesthetic (bupivacaine. 5% CC 12.5 mg) in 5 seconds in space The subarachnoid will be performed using a crowford needle with a high gauge 'number' of 25 by the paramedic method.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Peymaniyeh Hospital of Jahrom city
Full name of responsible person
Navid Kalani
Street address
Jahrom, Shahid Motahari Boulevard, Peymanieh Hospital
City
Jahrom
Province
Fars
Postal code
71677251542
Phone
+98 71 3525 5652
Email
Navidkalani@ymail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Solh joo Kavous
Street address
Jahrom, Shahid Motahari Boulevard, Jahrom University of Medical Sciences, Vice Chancellor for Research
City
Jahrom
Province
Fars
Postal code
7167758256
Phone
+98 71 2536 5231
Email
navidkalani@ymail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Jahrom University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Navid Kalani
Position
Research staff
Latest degree
Master
Other areas of specialty/work
Anesthesiology
Street address
Jahrom University of Medical Sciences
City
Jahrom
Province
Fars
Postal code
7167758256
Phone
+98 71 2536 5231
Email
k.navid@jums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Navid Kalani
Position
Research Expert
Latest degree
Master
Other areas of specialty/work
Anesthesiology
Street address
Jahrom, Shahid Motahari Boulevard
City
Jahrom
Province
Fars
Postal code
7167758256
Phone
+98 71 2536 5231
Email
k.navid@jums.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Navid Kalani
Position
Research Expert
Latest degree
Master
Other areas of specialty/work
Anesthesiology
Street address
Jahrom, Shahid Motahari Boulevard
City
Jahrom
Province
Fars
Postal code
7167758256
Phone
+98 71 2536 5231
Email
k.navid@jums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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