A clinical trial to compare the effect of the miniscrew-supported technique with conventional techniques in mandibular second molar uprighting in patients under orthodontic treatment

The comparison of the effect of the miniscrew-supported technique with conventional techniques in mandibular second molar uprighting in patients under orthodontic treatment

Clinical trial with control group, single-blind with parallel groups, randomized on 10 patients. Table of random numbers are used for randomization.

The patients are selected from those who refer to the Dental Clinic of Mashhad, Faculty of Dentistry, Mashhad, Iran. In this single-blind study, sealed opaque envelopes will be used to conceal the sequencing. The intervention group will receive the miniscrew-supported approach, and the control group will receive the conventional Melsen method for the uprighting of mandibular second molars. The person responsible for data collection is blind to the group allocation and the type of treatment.

Inclusion criteria: The patients who have already lost their first molars, those who are candidates for prosthetic treatment of the edentulous site, along with cases whose second molars are inclined at least 30 degrees. Exclusion criteria: Those with poor oral hygiene, history of using medications, systemic diseases, hormonal imbalance, and furcation involvement will be excluded from the study.

Intervention group will receive miniscrew-supported appliances for uprighting of mandibular second molars. Control group will receive conventional Melsen method for uprighting of mandibular second molars.

The time required for uprighting, speed of uprighting, the rate of tooth extrusion and the bone formation rate in the mesial.

In this study, simple randomization will be used by random number table based on SAS (statistical analysis system), software. A list of sequentially number 1 to 10 will be created. This list will assign numbers randomly by computer. Patients are randomly assigned according to the numbers of this list. To conceal, we use Allocation concealment, using non-transparent envelopes sealed with random sequences (Sequentially numbered, sealed, opaque envelopes). They are placed in order. In order to maintain the random sequence, numbering is done on the outer surface of the envelopes in the same way. Finally, the lids of the envelopes are glued and placed inside a box, respectively. At the beginning of the registration of participants, based on the order of entry of eligible participants in the study, one of the envelopes will be opened in order and the assigned group of the participant will be revealed.

The patients who refer to the Dental Clinic of Mashhad, Faculty of Dentistry, Mashhad, Iran, are selected as the participants of the study. In this single-blind study, sealed opaque envelopes will be used to conceal the sequencing. The person responsible for data collection is blind to the group allocation and the type of treatment.

The information obtained from the main outcomes of the study can be shared

6 months after publishing the results

The research data is exclusively accessible to the researchers working at universities and centers for scientific research

The research data is exclusively accessible to the researchers working at universities and centers for scientific research

Mostafa Entezari provides the data analysis to the applicants via email: mostafa.entezari91@gmail.com

Applicants can send emails to him and receive a response within a week.