The effect of a six-month combined care program with garlic supplementation on coagulation factors (INR, PTT, PT), Fibrinogen and platelets in middle-aged men with deep vein thrombosis (DVT)

Evaluation of the effect 6 months of combined training with garlic supplementation on coagulation factors (INR, PPT, PT), fibrinogen and platelets in men with DVT

Clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 40 patients. Excel software rand function was used for randomization.

This research was conducted experimentally with a clinical trial design. Subjects in this study included 40 middle-aged men aged 40 to 60 years with deep vein thrombosis (DVT) in Kermanshah. Subjects were available as a sample and met the inclusion criteria. In line with the research objectives, the subjects were randomly divided into four groups; 1. Combined exercise (resistance-aerobic) + garlic supplement (10 people), 2. Combined exercise (10 people), 3. Garlic supplement (10 people) and 4. Control group (10 people) by randomization method using Excel function rand functions were divided. In line with the objectives of the two-way blind study: both the researcher and the participants did not know about the supplement used in the supplement and placebo groups. .

Man Middle age 40 to 60 years With deep vein thrombosis No other diseases No motor disability

1. Combined exercise group (resistance - aerobic): Combined exercise was performed for 24 weeks with 3 sessions per week. 2. Garlic consumption group: Garlic supplement consumption in the present study was 1200 mg daily as one capsule per day and in the control group placebo (1200 mg starch) was used. Garlic extract capsules were obtained from the Ministry of Agriculture and the Ministry of Agriculture. 3. Combined exercise group and garlic consumption: included both combined exercise and the use of garlic supplements. 4. Control group: It was the use of placebo.

Combined exercise; Garlic

First, using the library, field and laboratory methods, measures were taken to collect information about the intervention. After identifying individuals with deep vein thrombosis (DVT) and selecting the research sample, the participants' consent to complete the study was completed. After obtaining the consent to participate in the research, the samples were randomly divided into 4 groups of 10 people: Group 1: Resistance (who performed the designed combined exercises) 2: Garlic consumption group (who consumed garlic according to the plan) 3: Combined exercise with garlic (who did the designed combined exercises and also consumed garlic) 4: Control (did not participate in any of the sports activities) Group 1, 8 weeks, did 3 sessions of combined exercise every week. All exercise programs, starting with the principle of overload, increasingly started from the first week and continued until the end of the eighth week. The experiments were performed in two stages, one day before the first training session (pre-test) and 48 hours after the last training session (post-test) in the eighth week of training, after 10 to 12 hours of fasting. It should be noted that all subjects, in addition to the intervention, continued to take warfarin tablets to the extent prescribed by the doctor for each person during the treatment period, and the amount and timing was determined by each person's doctor. The combined exercise program was performed for 24 weeks with a frequency of 3 days a week, combining aerobic and resistance exercises. Weight movements in 2 sets and 10 to 12 repetitions will include chest press, wire pull side pull, boat pull, leg press and bending and opening the thigh. Exercises started with 40% of a maximum repetition and lasted 22 minutes. In the aerobic section, the subjects trained for 22 minutes with an intensity of 40% of maximum heart rate (HRmax). At 4 weeks the intensity of the exercises was re-evaluated. At the beginning of the sessions they had 3 to 5 minutes of warm-up time and at the end of 3 to 5 minutes they had time to cool down

Both the researcher and the participants

After the study, I will make the result transparently available for publication in the Islamic Azad University, Kermanshah Branch.

After the end of the study in early August 2016

Islamic Azad University, Kermanshah Branch

To inform patients of deep vein thrombosis treated with warfarin about the risk of blood clots or leg bleeding regarding recovery after using one of these study methods

Hamed Saed

The request must be in writing and from the Islamic Azad University of Kermanshah