This study is a clinical trial in an easy and accessible method, then in the form of random block allocation, which is the most practical method of quadruple blocks in the blocking method. In this trial, the intervention group is group A and the control group is group B. In each block, waiting We have to be AABB. In this block layout, the combination of blocks as 1. AABB 2. ABAB 3. ABBA 4. BBAA 5. BABA 6, BAAB is divided. To make randomization completely unpredictable. Moving in a random number table should be from top to bottom, from left to right or right to left. According to these 6 blocking modes, we refer to the table of random numbers. For example, in the table of random numbers, the first block is AABB, which according to the table of random numbers is 1. AABB 1321. In this way, the number 1 of the intervention, the number 3 of the intervention, the number 2 of the control, the number 9 are deleted because the block modes are 6, then the number 1 is the control group and so on the other 9 blocks according to the random number table. We go and the samples are selected. From each of the studied groups and from the patients referring to the Iranian medicine clinics of the hospitals affiliated to Isfahan University of Medical Sciences who have the inclusion criteria, which will be done by block random allocation method in 2 control and test groups. we put. The experimental group takes herbal medicines under the supervision of a traditional medicine specialist and the dose of chemical medicines is adjusted by the doctor. The control group is taking oral medication under the supervision of a physician.