Evaluation of effect of preoperative oral carbohydrate on the blood glucose and hemodynamics in children under 3 years old undergoing elective inguinal surgeries

Evaluation of effect of preoperative oral carbohydrate on the blood glucose and hemodynamics in children under 3 years old undergoing elective inguinal surgeries

Clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 207 patients

In this study, a double-blind clinical trial was performed on 207 children under the age of three in three groups (first group: oral carbohydrates, second group: drinking water, third group: standards guidelines for fasting before surgery) equal to 69 patients in each group who were candidates for elective surgery. In Urmia Children's hospital, before induction of anesthesia and during surgery and recovery, patients' blood sugar will be measured by a glucometer. Mean arterial pressure and heart rate will be measured every 5 minutes for 20 minutes. Vomiting will be recorded at the time of induction of anesthesia and after withdrawal from anesthesia until discharge from recovery.

Inclusion criteria: Elective surgeries, American Society of Anesthesiologists (ASA) I and II, Age less than 3 years; Exclusion criteria: Emergency surgeries, Having heart, lung and liver diseases, Having metabolic diseases, Having diabetes, Glucose 6-phosphate deficiency

In the intervention group, 5 ml / kg of 20% dextrose solution made by Samen Pharmaceutical Company will be prepared orally for surgery in the pediatric surgery ward 2 hours before surgery, and in the control group, 5 ml / kg drinking water will be prescribed two hours before surgery. One group will fast according to pre-surgery standards.

Blood sugar, vomiting, mean arterial pressure, heart rate

Patients, using random allocation software, were randomly divided into control (fasting) and intervention (preoperative oral carbohydrate) groups. By selecting the simple randomization method in the randomization box and entering the determined total sample size in this software, numbers were given to the patients and the patients were allocated into two groups according to computer-generated numbers.

The patient is a child under 3 years old and has no information about the routine of receiving or not receiving carbohydrates before the operation and also the statistical analyzer will receive the data in code A and B for control and intervention groups, respectively.

Reporting of results as a published article

After publishing of article

Researchers

As published article

Corresponding author

If necessary access to the data can be done through the e-mail address of the corresponding author that will be written in the published article.