Evaluation of Legionella pnemophilia prevalence in patient with Ventilator associated pneumonia on two humidification system in intensive care unit of Shahid Bahonar hospital
Ventilator associated pneumonia is the respiratory infection in patient who have been intubated more than 48 hours and went under mechanical ventilator. Among different infectious causes of Ventilator associated pneumonia the Legionella pnemophilia infection is more important because the water supply of hospital are the most important source of this pathogen. Two system are used for humidifying and warming the inspiratory gas. These systems include heated humidifier and heat & moisture exchanger. To identifying the pathogenic cause of Ventilator associated pneumonia in ICU patients and also finding the way to decrease the incidence of this infection it is necessary to asses the prevalence of Ventilator associated pneumonia related to Legionella and then the role of two different humidifier as preventing agent be evaluated.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT201403255426N7
Registration date:2014-04-14, 1393/01/25
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2014-04-14, 1393/01/25
Registrant information
Name
Mehdi Ahmadinejad
Name of organization / entity
Anesthesiology department, Kerman University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 34 0223 5011
Email address
m.ahmadinejad@kmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Kerman University of Medical Sciences
Expected recruitment start date
2014-04-04, 1393/01/15
Expected recruitment end date
2014-06-05, 1393/03/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluation of Legionella pnemophilia prevalence in patient with Ventilator associated pneumonia on two humidification system in intensive care unit of Shahid Bahonar hospital
Public title
Evaluation of Legionella pnemophilia prevalence in patient with Ventilator associated pneumonia on two humidification system in intensive care unit of Shahid Bahonar hospital
Purpose
Prevention
Inclusion/Exclusion criteria
Including criteria: traumatic intubated patients between 17 to 70 years old.
Excluding criteria: patients who had been admitted with previous pneumonia diagnosis and have been shown sign of pneumonia less than 48 hours of admission. Patients with lung contusion or underling disease such as cystic fibrosis and COPD. Patients with renal failure and false positive and negative of urinary Legionella test and patient that receive antibiotics that affect Legionella. Patient who have positive urinary antigen when admitted to ICU.
Age
From 17 years old to 70 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
152
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Kerman University of Medical Sciences
Street address
Somaye cross road
City
Kerman
Postal code
Approval date
2014-02-26, 1392/12/07
Ethics committee reference number
501/92/K
Health conditions studied
1
Description of health condition studied
Legionella pneumonia
ICD-10 code
A48.1
ICD-10 code description
Legionnaires disease
Primary outcomes
1
Description
Legionella Urinary Antigen
Timepoint
48 h
Method of measurement
Urinary Antigen Kit
Secondary outcomes
empty
Intervention groups
1
Description
Application of Heated Humidifier and Heat and moisture exchanger
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Shahid Bahonar Hospital
Full name of responsible person
Mehi Ahmadinejad
Street address
Garani Street, Shahid Bahonar Hospital, ICU
City
Kerman
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Abbas Pardakhty
Street address
Somaye cross road
City
Kerman
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Kerman University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Kerman University of medical sciences
Full name of responsible person
Mehdi AhmadiNejad
Position
Assistant Professor
Other areas of specialty/work
Street address
Shahid Bahonar Hospital
City
Kerman
Postal code
Phone
+98 34 1223 5011
Fax
Email
m.ahmadinejad@kmu.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Kerman University of Medical sciences
Full name of responsible person
Mehdi AhmadiNejad
Position
Assistant Professor
Other areas of specialty/work
Street address
Shahid Bahonar Hospital
City
Kerman
Postal code
Phone
+98 34 1223 5011
Fax
Email
m.ahmadinejad@kmu.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Mehdi AhmadiNejad
Position
Assistant Professor
Other areas of specialty/work
Street address
Garani Street, Shahid Bahonar Hospital, ICU
City
Kerman
Postal code
Phone
+98 34 1223 5011
Fax
Email
m.ahmadinejad@kmu.ac.ir
Web page address
www.kmu.ac.ir
Sharing plan
Deidentified Individual Participant Data Set (IPD)