Protocol summary

Summary
Aim: The incidence of pressure sore in critically ill patients is high and this can be increased the risk of mortality. So this study designed to evaluation of the effect of topical oxygen therapy on pressure sore healing of traumatic critically ill patients. Design: A double blind clinical trial study on 80 eligible patients (inclusion criteria: 17-65 Y/O, without underlying medical conditions including organ failure, diabetes and burns. Exclusion criteria: systemic corticosteroid usage, chronic skin disease organ failure) will be done after assigned to two groups. Intervention: In the intervention group, the wound surface is in contact with moist oxygen at a rate of 10 liters per minute for 20 minutes, every day and then covered with a sterile gauze dressing. In the control group The routine dressing will be done. The intervening period will be 15 days. Outcomes: The area of pressure ulcer (length, width and depth) with Push scale and the stage of wound by direct observation are determined.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201602275426N9
Registration date: 2016-08-12, 1395/05/22
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2016-08-12, 1395/05/22
Registrant information
Name
Mehdi Ahmadinejad
Name of organization / entity
Anesthesiology department, Kerman University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 34 0223 5011
Email address
m.ahmadinejad@kmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research of Kerman University of Medical Sciences
Expected recruitment start date
2016-05-17, 1395/02/28
Expected recruitment end date
2016-11-18, 1395/08/28
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of Topical Oxygen on Wound healing of trauma patients admitted in Intensive Care Units of Kerman University of Medical Sciences
Public title
Effect of Topical Oxygen on healing of Pressure ulcers
Purpose
Treatment
Inclusion/Exclusion criteria
inclusion criteria: 17-65 Y/O; without underlying medical conditions including organ failure, diabetes and burns. Exclusion criteria: systemic corticosteroid usage; chronic skin disease; organ failure; patient death
Age
From 17 years old to 65 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 80
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Kerman University of Medical Sciences
Street address
Vice chancellor for research, Kerman University of Medical Sciences, Jahad Blvd, Somayye Crossroads, Shariaati St, Kerman
City
Kerman
Postal code
7619813159
Approval date
2016-05-17, 1395/02/28
Ethics committee reference number
IR.KMU.REC.1395.18

Health conditions studied

1

Description of health condition studied
Pressure ulcers
ICD-10 code
L89
ICD-10 code description
Decubitus ulcer and pressure area

Primary outcomes

1

Description
Stage of Pressure ulcer
Timepoint
Every three day
Method of measurement
Direct observation of wound

2

Description
The area of pressure ulcer (length, width and depth)
Timepoint
Every three day
Method of measurement
Push Scale

Secondary outcomes

empty

Intervention groups

1

Description
In the intervention group, the wound surface is in contact with moist oxygen at a rate of 10 liters per minute for 20 minutes, every day and then covered with a sterile gauze dressing.
Category
Treatment - Other

2

Description
In the control group only used routine dressing.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Bahonar Hospital
Full name of responsible person
Mehdi Ahmadinejad
Street address
Shahid Bahonar Hospital, Qarani St, Valiasr Crossroads, Shariaati St, Kerman
City
Kerman

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research of Kerman University of Medical Sciences
Full name of responsible person
Dr Pardakhti
Street address
Vice chancellor for research of Kerman University of Medical Sciences, Jahad Blvd, Somayye Crossroads, Shariaati St, Kerman
City
Kerman
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research of Kerman University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Mehdi Ahmadinejad
Position
Assistant Professor- Fellow of Intensive Care
Other areas of specialty/work
Street address
Shahid Bahonar Hospital, Qarani St, Valiasr Crossroads, Shariaati St, Kerman
City
kerman
Postal code
7619643797
Phone
+98 34132473825
Fax
Email
mehdia50@gmail.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Mehdi Ahmadinejad
Position
Assistant Professor- Fellow of Intensive Care
Other areas of specialty/work
Street address
Shahid Bahonar Hospital, Qarani St, Valiasr Crossroads, Shariaati St, Kerman
City
keman
Postal code
7619643797
Phone
+98 34132473825
Fax
Email
mehdia50@gmail.com
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Mehdi Ahmadinejad
Position
Assistant Professor-Fellow of Intensive Care
Other areas of specialty/work
Street address
Shahid Bahonar Hospital, Qarani St, Valiasr Crossroads, Shariaati St, Kerman
City
kerman
Postal code
Phone
+98 34 1226 0100
Fax
Email
mehdia50@ gmail.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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