Evaluation the effect of mouthwash containing propolis nanoparticles on plaque and gingival indices in fixed orthodontic patients.

Determining the effect of mouthwash containing propolis nanoparticles on plaque and gingival indices in fixed orthodontic patients

Clinical trial with control group, with parallel groups, double-blind, randomized, on 60 patients. The kitset.ir site was used for randomization.

The study will be performed on patients who refer to Babol Dental School for fixed orthodontic treatment. Plaque and gingival indices will be measured and recorded by the researcher in the periodontics department of the faculty in a basic state, and all patients are given three bottles of mouthwash that look exactly the same and the researcher and patient are not aware of the type of solution in it and the way of using it will be instructed. three weeks later, to evaluate the direction and extent of the effects of propolis nanoparticles, indices will be measured and recorded again.

Inclusion criteria: Age range 13-19 years, appropriate oral health conditions (Plaque Index≤ 2 and Gingival Index ≤ 2), complete and informed patient satisfaction. exclusion criteria: the presence of any systemic disease, pregnancy and lactation for female participants, Smoking and alcohol consuming, periodontal disease, sever gingivitis and Severe plaque accumulation, history of any allergies to propolis or honey derivatives, history of taking antibiotics from two weeks and any mouthwash from one month before the intervention.

After prophylaxis of all 60 patients' teeth and measurement of plaque and gingival indices of Ramford teeth and placement of orthodontic appliance in their mouth, all people will enter the intervention phase.

Plaque index ; Gingival index

People are divided into two groups of 30 people, so that in each group there will be 15 girls and 15 boys. The site kitset.ir is used to randomize the samples. In the Kitset site, from the number toolbox, select the option to generate random numbers. Then we request the production of 30 pieces from 1 to 30 in a non-sequential and non-repetitive way. The series of random numbers generated in the result box will be considered as the case number of the referring boy, the first 15 numbers will be in the case group and the next 15 numbers will be in the control group. We do the same for the referral girls again; In this way, we request the production of 30 pieces from 1 to 30 again without order and without repetition. The series of random numbers generated in the result box will be considered as the case number of the referring girl, the first 15 numbers will be in the case group and the next 15 numbers will be in the control group.

Both types of mouthwashes are packaged with the same appearance so that the patient and the researcher do not know the type of solution in the container; One type of mouthwash will belong to group A and the other to group B‌.

There is no more information.