The main goal of the study is: evaluating the effect of vaginal cleansing with betadine before cesarean delivery on postoperative infectious morbidity in women with premature rupture of the membranes.
The specific goals of the study are to compare fever, endometritis, and infectious morbidity related to the surgical wound between the two group with and without cleansing with betadine.
The use of the study is to use this method if it would be effective.
100 pregnant women candidate of non-emergent cesarean section with premature rupture of membrane are randomly divided into two equal intervention and control groups. All patients are undergone cesarean section with phanensteil and kerr incision. Then the follow up of the patients will be done weekly to two weeks after cesarean and all the study variables will be evaluated with each visit. The two groups will be identical about age parity, gravidity, the time from the beginning of ruptured membrane. In the beginning, the following person will be unaware of the groups of the patients.
inclusion criteria: history of ruptured membrane; candidates of cesarean with phanenshteil incision; those who have no more than two vaginal examinations. exclusion criteria: allergy to betadine; chorioamnionitis; active genital herpes; emergency cesareans; more than two vaginal examinations; more than 12 hours past the ruptured membranes; more than 1.5 hours duration of the operation.
After randomization of patients into two groups, in the interventional group, the vagina is rinsed with 10% betadine for 30 seconds just before cesarean. In the control group nothing is done. All the patients are given 1g cephazoline before cesarean and 6 hour later for prophylaxis. They are followed weakly for two weeks. All the variables including, age; parity; gravidity; the interval from the ruptured membrane; fever(temperature=or>38 degree, 24 hours after delivery; endometritis(uterus tenderness with fever, requiring antibiotics; wound complications(including dehiscence, infection requiring antibiotics, debridement) will be evaluated with each visit.