Evaluation of orthoptics thraputic effects using Major Amblyoscope (office-based therapy) as well as active vision therapy using Enhancement of binocular vision software and red-green glasses (home-based therapy) to improve controlling of intermittent exotropia

Evaluation of the effect of orthopthic treatment using major amblyoscope and also active vision therapy using binocular enhancement software and red-green glasses in improving intermittent exotropic control

Clinical trial with intervention group using orthopthic exercises and binocular enhancement software and control group with conventional patch therapy treatment, simple randomized, phase 3 on 60 patients

Khatam Al-Anbia Ophthalmology Hospital, Mashhad The clinical trial is Superiority, Parallel and one-sided blind After eye examinations, we sit behind the major amblyoscope and use different slides such as simultaneous perception, flat fusion and fusion. At home, exercises such as removing suppression aand pencil push up, Practice with 2pencils, Marsen dot, thread and bead are done With good control after 1month, follow-up for 6 months, and after there was no report of XT, the exercises are slowly reduced

- 5- 18 years Exotropia less than 40 prisms without vertical deviation or pattern no eye surgery, amblyopia & structural disorders and high refractive errors Gaining consent of the parents and child cooperation Grade 2, 3 & 4 on the Mohney and Holms IXT Control Scale - no cooperation of child

In the intervention group, anti-suppression and fusion therapy exercises are performed by major amblyoscope and binocular enhancement software and red-green glasses 22 sessions and two 20-min sessions per week by an orthopthist. Playing computer games using filter glasses for 30 min twice a day for 5 days a week for 4 weeks and then 2 days a week for 8 weeks for 3 months

Intermittent and fusion state exotropic control based on the Mohney and Holmes Intermittent Exotropia Control Scale system evaluates this score before the intervention and then during subsequent follow-up times

Simple individual randomization will be done using a random number table and the website WWW.Randomization.com. Random concealment will be done using packets in the package in which the envelopes are prepared by a member of the research team and the random numbers extracted from WWW.Randomization.com are prepared and printed and They are placed inside the envelope and will be closed in the envelopes and its contents will not be visible from the outside; Then, first the purpose of the study will be explained to the person who has the inclusion criteria and the person will sign the informed consent form and take an envelope and then open it and based on the contents of the envelope in the intervention or control group will enter.

Outcome assessor means that the person who visits the patient and evaluates and records the consequences is not aware of how the patients are grouped. In other words, the outcome assessor of the patient who visits and evaluates the outcome is not aware that the patient is Comments are in the control group or in the intervention group.

Individual Participant Data Set (IPD): all collected deidentified IPD could be shared.

Starting 6 months after publication

People working in academic institutions

No further criteria.

Mohammad Etezad Razavi: Khatam al-Anbia Eye Hospital, Aboutaleb Intersection, Mashhad, Iran etezadm@mums.ac.ir , 00989155199624

With a reasonable request, the data would be shared via email.