Protocol summary

Study aim
Comparison of EMG-NCV characteristics between the two groups
Design
After giving the necessary explanations, written consent is obtained from the mentioned patients, and then they are treated with balance or aerobic exercises in one of the two groups in a simple random manner and in a block method.
Settings and conduct
This is randomized clinical trial.
Participants/Inclusion and exclusion criteria
Inclusion criteria include diabetics patient between the ages of 30 and 65 who are able to stand and walk independently without any assistive devices, and Electrodiagnostic tests have confirmed the presence of diabetic Neuropathy. Exclusion criteria include people with diabetic foot ulcers, uncontrolled blood sugar, inner ear infection, neurological diseases (other than neuropathy) or other disorders of balance, a history of recurrent ankle sprains in the past year, severe pain It is a disturbance of balance and the presence of any disturbing factor of balance other than diabetic neuropathy.
Intervention groups
Diabetic patients are divided into two groups of balance and aerobic exercise. Before the intervention, patients are tested for EMG-NCV and then they are given balance or aerobic exercise 3 days a week for 8 weeks. After 8 week EMG-NCV tests are taken again from patients.
Main outcome variables
Comparison of emg-ncv characteristics in diabetic patients into two groups of balance and aerobic exercise

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20180416039324N4
Registration date: 2021-12-01, 1400/09/10
Registration timing: prospective

Last update: 2021-12-01, 1400/09/10
Update count: 0
Registration date
2021-12-01, 1400/09/10
Registrant information
Name
Sirous Azizi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 4382 3476
Email address
s.azizi@ajaums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-12-17, 1400/09/26
Expected recruitment end date
2022-04-23, 1401/02/03
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effectiveness of balance exercise in comparison with aerobic exercise on electro diagnostic parameters in patient with diabetic peripheral neuropathy
Public title
Effectiveness of balance exercise in comparison with aerobic exercise on electro diagnostic parameters in patient with diabetic peripheral neuropathy
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Diabetics patient between the ages of 30 and 65 are able to stand and walk independently without any assistive devices, are able to walking independently without any assistive devices, electrodiagnostic tests have confirmed the presence of diabetic neuropathy
Exclusion criteria:
Diabetic ulcers in the legs, uncontrolled blood sugar, inner ear infection, neurological diseases (other than neuropathy) or other disorders of balance, history of recurrent ankle sprains in the past year, severe disturbing balance presence Any factor that disturbs the balance other than diabetic neuropathy
Age
From 30 years old to 65 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 66
Randomization (investigator's opinion)
Randomized
Randomization description
Patients are randomly assigned to balance or aerobic exercise in one of two groups using block randomization. To randomly assign two groups with 33 participants in each group (66 patients in total), we use block randomization with different block sizes. The size of the blocks is a multiple of 3 and a divisor of 66 (3,6,9). Initially, the size of the blocks is randomly selected. Then for each block, different permutations are determined for the size of the equal group. Finally, one of the permutations is randomly selected. Random numbers are generated using a computer in an independent statistical unit.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of mical university for the islamic republic of iran s Army
Street address
Imam Reza hospital, Etemad zade street, Fatemi street, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1411718546
Approval date
2021-05-15, 1400/02/25
Ethics committee reference number
IR.AJAUMS.REC.1400.025

Health conditions studied

1

Description of health condition studied
DIABETS
ICD-10 code
E08
ICD-10 code description
Diabetes mellitus due to underlying condition

Primary outcomes

1

Description
emg-ncv
Timepoint
Before intervention -8 weeks after intervention
Method of measurement
Using a emg-ncv machine

Secondary outcomes

empty

Intervention groups

1

Description
ntervention group 1 is treated with aerobic exercise in 24 sessions (3 days a week for 8 weeks).
Category
Treatment - Other

2

Description
Intervention group: Intervention group 2 is treated with balance exercises in 24 sessions (3 days a week for 8 weeks).
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam Reza Hospital in Tehran
Full name of responsible person
Fatemeh Vashaei
Street address
Imam Reza hospital, Etemad zade street, Fatemi street
City
Tehran
Province
Tehran
Postal code
1411718546
Phone
+98 21 8609 6350
Email
f_vashaei@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Artesh University of Medical Sciences
Full name of responsible person
Fatemeh Vashaei
Street address
Imam Reza hospital, Etemad zade street, Fatemi street
City
Tehran
Province
Tehran
Postal code
1411718546
Phone
+98 21 8609 6350
Email
f_vashaei@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Artesh University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Artesh University of Medical Sciences
Full name of responsible person
Fatemeh Vashaei
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Physical Medicine
Street address
Imam Reza hospital, Etemad zade street, Fatemi street
City
Tehran
Province
Tehran
Postal code
1411718541
Phone
+98 21 8609 6350
Email
f_vashaei@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Artesh University of Medical Sciences
Full name of responsible person
Fatemeh Vashaei
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Physical Medicine
Street address
Imam Reza hospital, Etemad zade street, Fatemi street
City
Tehran
Province
Tehran
Postal code
1411718541
Phone
+98 21 8609 6350
Email
f_vashaei@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Artesh University of Medical Sciences
Full name of responsible person
Fatemeh Vashaei
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Physical Medicine
Street address
Imam Reza hospital, Etemad zade street, Fatemi street
City
Tehran
Province
Tehran
Postal code
1411718541
Phone
+98 21 8609 6350
Email
f_vashaei@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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