Probiotics could have benefits on oral health, partially through modifying oral cavity microflora. The purpose of this study was to investigate the effect of consumption of a commercial probiotic yogurt on oral halitosis.This uncontrolled clinical trial was conducted on 44 volunteers suffering from halitosis with oral cavity origin. The subjects were given 200 ml probiotic yogurt daily for a period of two weeks. One examiner evaluated subjects’ mouth odor at baseline and after two weeks using organoleptic assessment (a 5 point scale: 0= no, 1= brief, 2= medium, 3=severe, and 4= very severe) at 10 and 50 cm distances.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT201407115570N7
Registration date:2014-09-27, 1393/07/05
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-09-27, 1393/07/05
Registrant information
Name
Parichehr Behfarnia
Name of organization / entity
Isfahan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 31 1666 1707
Email address
behfarnia@dnt.mui.ac.ir
Recruitment status
Recruitment complete
Funding source
Isfahan University of Medical Sciences
Expected recruitment start date
2013-12-01, 1392/09/10
Expected recruitment end date
2014-03-31, 1393/01/11
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The Effect of Probiotic Yogurt on Oral Halitosis by Organoleptic Assessment
Public title
The Treatment effect of Consumption of a Commercial Probiotic Yogurt on Oral Halitosis
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: male or female who suffer from halitosis with oral cavity origin
exclusion criteria: systemic disorder, use of chewing gum(xylitol), use of antibiotic or fluoride, existing of oral ulcer
Age
No age limit
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
44
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethic Committe of Isfahan University Of Medical Sciences
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Postal code
8174673461
Approval date
2013-08-23, 1392/06/01
Ethics committee reference number
393429
Health conditions studied
1
Description of health condition studied
halitosis
ICD-10 code
KO5
ICD-10 code description
gingivitis and periodontal disease
Primary outcomes
1
Description
oral malodor assessment at 10 cm distances
Timepoint
2 weeks after probiotic yuogart consuption
Method of measurement
organoleptic assesment
Secondary outcomes
1
Description
assessment of oral malodor at 50 cm distance
Timepoint
2 weeks after probiotic yougart consuption
Method of measurement
organoleptic assesment
Intervention groups
1
Description
daily use of 200g probiotic yogurt for 2 weeks
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Dental School, Isfahan University Of Medical Sciences
Full name of responsible person
Parichehr Behfarnia
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice Chancellor for Research, Isfahan University Of Medical Sciences
Full name of responsible person
Omid Savabi
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Grant name
تحقیقاتی
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice Chancellor for Research, Isfahan University Of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Isfahan University of Medical Sciences
Full name of responsible person
Parichehr Behfarnia
Position
assistant professor
Other areas of specialty/work
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Postal code
8174673461
Phone
+98 31 3792 2870
Fax
+98 31 3668 7080
Email
behfarnia@dnt.mui.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Isfahan University of Medical Sciences
Full name of responsible person
Parichehr Behfarnia
Position
Assistant Professor
Other areas of specialty/work
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Postal code
8174673461
Phone
+98 31 3792 2870
Fax
+98 31 3668 7080
Email
behfarnia@dnt.mui.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Isfahan University Of Medical Sciences
Full name of responsible person
Parichehr Behfarnia
Position
Assistant Professor
Other areas of specialty/work
Street address
Dental School, Isfahan University Of Medical Sciences ,Hezar Jarib St.
City
Isfahan
Postal code
8174673461
Phone
+98 31 3792 2870
Fax
+98 31 3668 7080
Email
behfarnia@dnt.mui.ac.ir
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)