Protocol summary

Study aim
To compare the impact of microdebrider assisted inferior turbinoplasty vs inferior turbinate cauterization on the quality of life of children.
Design
A randomized double-blind clinical trial study with a control group, with parallel design on 54 patients. Block randomization method will be used for randomization.
Settings and conduct
Shahid Dastgheib hospital affiliated to Shiraz University of Medical Sciences
Participants/Inclusion and exclusion criteria
Patients under 18 years of age with inferior turbinate hypertrophy who complained of nasal congestion and rhinorrhea in rhinoscopy and did not respond well to oral or topical corticosteroids, antihistamines, and other conservative methods, who were candidate for turbinate reduction surgery included in this study.
Intervention groups
first: microdebrider assisted inferior turbinoplasty second: inferior turbinate cauterization
Main outcome variables
quality of life of children

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20131020015083N3
Registration date: 2021-11-30, 1400/09/09
Registration timing: registered_while_recruiting

Last update: 2021-11-30, 1400/09/09
Update count: 0
Registration date
2021-11-30, 1400/09/09
Registrant information
Name
Amir Hossein Babaei
Name of organization / entity
Shiraz University Of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 917 739 5073
Email address
babaei@sums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-11-23, 1400/09/02
Expected recruitment end date
2022-08-23, 1401/06/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
To compare the impact of microdebrider assisted inferior turbinoplasty vs inferior turbinate cauterization on the quality of life of children
Public title
To compare the impact of microdebrider assisted inferior turbinoplasty vs inferior turbinate cauterization
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
inferior turbinate hypertrophy nasal congestion Existence of rhinorrhea Failure to respond to medications including oral or topical corticosteroids, antihistamines
Exclusion criteria:
Age more than 18 years Adenoid hypertrophy Nasal polyps Severe deviation of the nasal septum
Age
To 18 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Outcome assessor
  • Data analyser
Sample size
Target sample size: 27
Randomization (investigator's opinion)
Randomized
Randomization description
Participants were randomly assigned to microذeprider assisted inferior turbinoplasty (number 0 in select case) or inferior turbinate cauterization (number 1 in select case) groups (1: 1 ratio) using random numbers which were generated through computerized block randomization using SPSS software version 23. To reduce selection bias and confounding factors, randomization was performed by a single appointed researcher who did not participate in data collection.
Blinding (investigator's opinion)
Double blinded
Blinding description
patients, outcome assessor, and statisticians who analyzed the data were unaware of the intervention and allocation of treatments until the statistical analysis was complete.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Shiraz University of Medical Sciences
Street address
Zand Street
City
shiraz
Province
Fars
Postal code
71348-14336
Approval date
2021-10-30, 1400/08/08
Ethics committee reference number
IR.SUMS.MED.REC.1400.401

Health conditions studied

1

Description of health condition studied
children with hypertrophy of nasal turbinates
ICD-10 code
J34.3
ICD-10 code description
Hypertrophy of nasal turbinates

Primary outcomes

1

Description
Patients' quality of life
Timepoint
1, 3 and 6 months after surgery
Method of measurement
SNOT-22 Questionnaire

2

Description
Presence of crust in nasal cavity
Timepoint
Up to 1 week after surgery
Method of measurement
Anterior rhinoscopy

Secondary outcomes

1

Description
Postoperative nasal bleeding
Timepoint
Up to 1 week after surgery
Method of measurement
Anterior rhinoscopy

2

Description
Facial pain
Timepoint
Up to 1 week after surgery
Method of measurement
Question from the patient

3

Description
Bad smell in nose
Timepoint
Up to 1 week after surgery
Method of measurement
Question from the patient

Intervention groups

1

Description
Intervention group: microdebrider assisted inferior turbinoplasty
Category
Treatment - Surgery

2

Description
Intervention group: inferior turbinate cauterization
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Dastgheib Hospital
Full name of responsible person
Dr. Tayebeh Kazemi
Street address
Hafez street
City
Shiraz
Province
Fars
Postal code
71456-3769
Phone
+98 71 3228 8064
Fax
Email
tayyebe.kazemi@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr. Abbas Rezaeianzadeh
Street address
Zand street
City
Shiraz
Province
Fars
Postal code
7134844119
Phone
+98 71 3235 7282
Fax
+98 71 3235 7282
Email
vcrdep@sums.ac.ir
Grant name
Grant code / Reference number
22804
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shiraz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr. Tayebeh Kazemi
Position
Assistant professor
Latest degree
Specialist
Other areas of specialty/work
Ear, Nose, and Throat
Street address
khalili street
City
Shiraz
Province
Fars
Postal code
7193636981
Phone
+98 71 3629 1470
Email
tayyebe.kazemi@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr. Akram Rahmanipour
Position
resident
Latest degree
Medical doctor
Other areas of specialty/work
Ear, Nose, and Throat
Street address
Khalili street
City
Shiraz
Province
Fars
Postal code
7193636981
Phone
+98 71 3629 1470
Email
salmanp445@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr Amirhossein Babaei
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Ear, Nose, and Throat
Street address
Zand blvd, Shiraz, Iran
City
Shiraz
Province
Fars
Postal code
7196741475
Phone
+98 917 739 5073
Email
babaei@sums.ac.ir
Web page address
https://www.researchgate.net/profile/Amirhossein-Babaei

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
all collected deidentified IPD
When the data will become available and for how long
starting 6 months after publication
To whom data/document is available
only available for people working in academic institutions.
Under which criteria data/document could be used
there is no specified criteria
From where data/document is obtainable
corresponding author (salmanp445@gmail.com; 09179871643)
What processes are involved for a request to access data/document
the request should be sent by email (containing personal and professional information), describing their study protocol, after approving their identity and proposal, the data will be sent by email.
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