Forty patients aged 2 months to 18 years with Status Epilepticus and resistant to therapy with Phenobarbital, Phenytoin and Midazolam, admitted to PICU are enrolled in the study. Consecutive odd and even numbers are assigned to them. Propofol and Thiopental are administered to odd and even numbered, respectively. Propofol is given as a bolus of 1-2 mg/kg followed by continuous infusion of 1-2 mg/kg/hr. If necessary, the dose is raised by 2 mg/kg/hr every 10 minute to a maximum of 8 mg/kg/hour. Thiopental is given as a bolus of 1 mg/kg followed by continuous infusion of 2 mg/kg/hour. If necessary, the dose is raised by 2 mg/kg/hour till maximum dose of 10mg/kg/hour. If convulsion is not controlled after receiving the maximum dose of the drug, the patient will be put on another option. The goal of treatment with Propofol is disappearance of clinical seizures and epileptic activity on the EEG for 12-24 hours. The goal of treatment with thiopental is complete control of seizures for 12-24 hours with a burst suppression pattern on the EEG. Side effects are regularly monitored, and infusion is stopped if side effects emerged. In patients treated with Propofol, special attention is paid to Liver function tests, triglycerides, Creatine Kinase, and blood gas analyses. In patients treated with thiopental, special attention is paid to respiratory, circulatory, and infectious complications.