Protocol summary

Study aim
Clinical evaluation of marginal adaptation of three-unit metal ceramic restoration fabricated using conventional impression technique and the new CAD/CAM technology in a randomized clinical trial study
Design
Clinical trial with parallel groups, double-blind, randomized, on 33 patients. Excel software rand function was used for randomization.
Settings and conduct
Patients are visited at the dentist's office to assess the outcome. Part of the work is done in the research center laboratory, but the patient does not need to be present. Both the patient and the outcome assessor will be unaware of how the allocation process is done.
Participants/Inclusion and exclusion criteria
Periodontal health, Teeth: need restoration, have enough periodontal support, have sufficient length of preparation, have a positive long-term prognosis The patient is willing to participate in our study , Systemic disease Poor oral hygiene Periodontitis, severe gingivitis and high caries activity Obvious signs and symptoms of bruxism or clenching Periodontal surgery required before preparation Second or higher degree of mobility, clinical signs
Intervention groups
1. Includes 11 patients in which two basic teeth are examined in each patient. They receive the cobalt chrome three-unit restoration fabricated by the traditional casting method. 2. Includes 11 patients in which two basic teeth are examined in each patient. They receive the cobalt chrome three-unit restoration fabricated by CAD / Milling method from hard metal blocks. 3. Includes 11 patients in which two basic teeth are examined in each patient. They receive the cobalt chrome three-unit restoration fabricated by CAD / Ceramill Sintron method from soft metal blocks.
Main outcome variables
The main outcome includes marginal restoration compliance and the secondary consequences include internal and occlusal compliance

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20160213026538N7
Registration date: 2022-01-28, 1400/11/08
Registration timing: prospective

Last update: 2022-01-28, 1400/11/08
Update count: 0
Registration date
2022-01-28, 1400/11/08
Registrant information
Name
Hedaiat Moradpoor
Name of organization / entity
Kermanshah University of Medical Siences
Country
Iran (Islamic Republic of)
Phone
+98 83 3729 6910
Email address
h.moradpour@kums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-01-30, 1400/11/10
Expected recruitment end date
2022-05-20, 1401/02/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Clinical evaluation of marginal adaptation of three-unit metal ceramic restoration fabricated using conventional impression technique and the new CAD/CAM technology in a randomized clinical trial study
Public title
Clinical evaluation of marginal adaptation
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
Periodontal health, plaque index and BOP should be below 20% before prosthetic treatment Abutment teeth require restoration Abutment teeth Have enough periodontal support for three-unit restoration. Abutment Teeth have sufficient length of preparation Abutment teeth have a positive long-term prognosis The patient is willing to participate in our study and sign the consent form
Exclusion criteria:
The patient has a systemic disease that affects clinical outcomes The patient is unwilling or unable to maintain adequate oral hygiene The patient has periodontitis, severe gingivitis and high caries activity The patient has obvious signs and symptoms of bruxism or clenching Abutment teeth require periodontal surgery before preparation Abutment teeth have second or higher degree of mobility Abutment teeth have clinical signs
Age
From 22 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Outcome assessor
Sample size
Target sample size: 33
Randomization (investigator's opinion)
Randomized
Randomization description
A table of random numbers is used for randomization. In Excel software environment, four-digit codes are generated using the RANDBETWEEN command. Each patient is assigned a 4-digit code. If the last digit on the right is 1, 2 or 5, the patient is in the casting group, and if the last digit is 6, 3 or 8, the patient is assigned to the CAD Milling group. And if it is 7, 9 or 4, it is assigned to the CAD Ceramill Sintron group (Number zero is not considered). All codes are Written on papers and are kept in specific envelopes, which are randomly arranged. Registration and evaluation of entrance criteria is done by the secretary. When all the criteria for entering the study have been reviewed and the patient's information have been recorded, the secretary in charge of conducting the study will give one of these envelopes to the doctor. The doctor will decide on the treatment plan based on the specified code. Random sequencing is performed by a statistical and epidemiological consultant using Excel software. The secretary only cooperates to conduct the study and has no information about the study hypothesis or the group codes. The outcome assessor also has no information on how patients are coded and assigned, but the doctor doing the assignment of intervention is aware of the group codes.
Blinding (investigator's opinion)
Double blinded
Blinding description
This study is a double-blinded trail. Patients will not be aware of the process of fabricating restorations and will also not be aware of which study group they are in. Also, the person in charge of evaluating the outcome has no information about how restorations are made. Therefore, both the patient and the outcome assessor will be unaware of how the allocation process is done
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

1

Registry name
Secondary trial Id
Registration date
empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Kermanshah University of Medical Sciences
Street address
Shahid Beheshti Boulevard - Central Building of Kermanshah University of Medical Sciences
City
Kermanshah
Province
Kermanshah
Postal code
6714869914
Approval date
2022-01-24, 1400/11/04
Ethics committee reference number
IR.KUMS.REC.1400.739

Health conditions studied

1

Description of health condition studied
Marginal mismatch
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Marginal restoration adaptation
Timepoint
Before and after veneering
Method of measurement
1. Parallel bitwing radiograph 2. Probe 3. Silicone replica

Secondary outcomes

1

Description
Internal and occlusal adaptation
Timepoint
Before and after veneering
Method of measurement
1. Parallel byte wing radiography 2. Probe 3. Silicone replica

Intervention groups

1

Description
Intervention group: Traditional casting method
Category
Prevention

2

Description
Intervention group: CAD / Milling method from hard metal blocks
Category
Prevention

3

Description
Intervention group: CAD / Ceramill Sintron method from soft metal blocks
Category
Prevention

Recruitment centers

1

Recruitment center
Name of recruitment center
Dr. Hedayat Moradpour's dental office
Full name of responsible person
Hedaiat Moradpour
Street address
Kashani St., Dabirazam Alley, Arshia Building, Unit 11
City
Kermanshah
Province
Kermanshah
Postal code
6713739988
Phone
+98 83 3729 6920
Email
hedaiat.moradpoor@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Kermanshah University of Medical Sciences
Full name of responsible person
Farid Najafi
Street address
Vice Chancellor for Research Kermanshah University of Medical Sciences, Central building, Shahid Beheshti Boulevard, Kermanshah
City
Kermanshah
Province
Kermanshah
Postal code
6715847141
Phone
+98 83 3729 6591
Email
fnajafi@kums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Kermanshah University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Kermanshah University of Medical Sciences
Full name of responsible person
Vahid Vahedi
Position
Under graduated Student of Dentistry
Latest degree
Bachelor
Other areas of specialty/work
Dentistry
Street address
The school of Dentistry, shariati Street, Kermanshah
City
Kermanshah
Province
Kermanshah
Postal code
6713954658
Phone
+98 83 3724 8531
Email
v.vahedidds@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Kermanshah University of Medical Sciences
Full name of responsible person
Hedaiat Moradpour
Position
Prosthodontics Specialist
Latest degree
Specialist
Other areas of specialty/work
Dentistry
Street address
Department of Prosthodontics, The school of Dentistry, Kermanshah University of Medical Sciences , Iran
City
Kermanshah
Province
Kermanshah
Postal code
6713954658
Phone
+98 83 3729 6910
Fax
Email
h.moradpour@gmail.com
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Kermanshah University of Medical Sciences
Full name of responsible person
Vahid Vahedi
Position
Under graduated Student of Dentistry
Latest degree
Bachelor
Other areas of specialty/work
Dentistry
Street address
The school of Dentistry, shariati Street, Kermanshah
City
Kermanshah
Province
Kermanshah
Postal code
6713954658
Phone
+98 83 3724 8531
Email
v.vahedidds@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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