Fabrication and clinical study of the effect of lavender chewing gum on salivary Streptococcus mutans, salivary pH, plaque index, and gingival bleeding

Fabrication and clinical study of the effect of lavender chewing gum on salivary Streptococcus mutans, salivary pH, plaque index, and gingival bleeding

A clinical trial with the control group, with parallel groups, double-blind, randomized, with 57 participants. For randomization, sealed envelopes with predefined codes (code A: intervention and code B: control) that will be placed inside the bag will be used. Participants randomly select an envelope. After identifying the code, appropriate treatment is considered. The evaluator and the participant are not aware of any of the treatments.

Study of a double-blind, randomized (by random number table), with control and intervention group (lavender gum), on the staff of Tabriz University of Medical Sciences. Consume lavender gum for 2 weeks and then dental plaque and bacterial status of saliva will be checked. The evaluator and participant are not aware of the type of treatment.

Inclusion: Participants do not have systemic disease, Have acceptable oral hygiene (do not have a clear mass and plaque), Age range 18 to 65 years, People who have an average of 22 teeth, Do not be pregnant or breastfeeding Exclusion: Taking antibiotics or drugs that affect saliva, Use of an oral appliance, Smoking, and alcohol consumption, People with temporomandibular joint problem

The staff of Tabriz University of Medical Sciences will be studied in two groups, the intervention (Chewing gum containing lavender extract) and the control (Chewing gum without lavender extract). The amount of chewing gum used by each person daily will be six pieces, one after each meal and three pieces during the day for at least 15 minutes for 14 consecutive days.

Plaque index and bleeding gums, number of Streptococcus mutans saliva colonies, saliva pH

The study will be conducted randomly among the staff of Tabriz University of Medical Sciences. The method of randomization is simple and its unit is individual. Randomization will be performed in such a way that the first group is identified by code A (intervention) and the second group by code B (control) and will be placed inside sealed envelopes; The envelopes are then placed in a bag and shaken. After returning to the place, people put their hands inside the bag and randomly take out an envelope. After viewing the code, the treatment will be given to the patient. The evaluator and participant are not aware of the type of groups.

The present study is two-way blind and the outcome assessor, data analyst, and study participant are not aware of the type of groups. The researcher and outcome assessors are not aware of the randomization and segmentation of the Chewing gums among the participants and do not intervene. To blind the participants to the taste of chewing gum, the same flavoring is added to both types of chewing gum.