Protocol summary

Study aim
Determining the effect of vaginal pessary placement on quality of life, sexual self-efficacy and in women with uterine prolapse
Design
The present study is a quasi-experimental study of pre-test-post-test type. 72 individuals will be selected to participate in the study using available sampling and will be randomly assigned to the intervention and control groups. The number of sample volumes in each group is 30 people and 36 people in each group, taking into account the 10% drop. There is no blinding. After collecting data, questionnaires will be extracted and in SPSS software.
Settings and conduct
Research community of women aged 45-60 years with uterine prolapse in Tehran. Research environment of Arash Hospital and Taleghani Hospital and private offices of physicians. The questionnaire is given once before the intervention and once 8 weeks later. no action is taken for the control group.
Participants/Inclusion and exclusion criteria
-Inclusion criteria : Women aged 45-60 years، Married women living together with their husbands، Literacy، Willingness and interest in participating in the study، Minimum grade 1 prolapse، Tendency to use pessary instead of surgery، Having pessary placement conditions، Lack of vaginitis -Exclusion criteria: People who refuse to cooperate in filling out the questionnaire and continuing the study، Increased vaginal discharge and infection and the patient's unwillingness to continue using the pessary.
Intervention groups
The intervention group is those who have prolapse or do not want surgery or have contraindications for surgery due to the underlying disease and their choice is a pessary. The control group is those who have uterine prolapse and do not want to have a pessary implant.
Main outcome variables
Improving quality of life and sexual efficiency; pessary clinical care management;Promoting sexual satisfaction in women with prolapse

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20110425006284N17
Registration date: 2022-07-27, 1401/05/05
Registration timing: registered_while_recruiting

Last update: 2022-07-27, 1401/05/05
Update count: 0
Registration date
2022-07-27, 1401/05/05
Registrant information
Name
Maryam Modarres
Name of organization / entity
Tehran university of Medical sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 6656 8142
Email address
modarres@sina.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-04-21, 1401/02/01
Expected recruitment end date
2022-11-21, 1401/08/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of vaginal pessary implantation on quality of life, sexual self-efficacy and clinical management of care in women with uterine prolapse
Public title
The effect of pessary on the clinical care of women with prolapse
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Women aged 45-60 years Married women and women living together with their husbands Literacy Willingness and interest in participating in the study Minimal first-degree prolapse Tendency to use pessary instead of surgery Lack of vaginitis
Exclusion criteria:
Having vaginal discharge and infection and the patient's unwillingness For pessary placement..
Age
From 45 years old to 60 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 72
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Tehtan University of Medical Sciences
Street address
Tohid Square, Dr. Mirkhani St. (Eastern Nusrat),
City
Tehran
Province
Tehran
Postal code
1419733171
Approval date
2022-04-10, 1401/01/21
Ethics committee reference number
IR.TUMS.FNM.REC.1401.002

Health conditions studied

1

Description of health condition studied
Uterine prolapse
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Correction of uterine prolapse
Timepoint
At the beginning of the study (before the intervention) and once 8 weeks after the intervention
Method of measurement
Pelvic Organ Prolapse Quantification (POP-Q) System

Secondary outcomes

1

Description
Quality of life and sexual self-efficacy and management of patient clinical care
Timepoint
Once at the beginning of the study (before the intervention) and once 8 weeks after the intervention
Method of measurement
Quality of Life Questionnaire in Women with Prolapse (P-QOL), Vaziri and Lotfi Self-Efficacy Questionnaire, PGI Three-Question Scale Questionnaire, Researcher-Managed Clinical Care Questionnaire

Intervention groups

1

Description
Intervention group: The intervention group are those who have uterine prolapse and tend to have a pessary implantation and meet the inclusion criteria. For this group, a silicone device called a pessary is used to treat uterine prolapse. This device is available in different sizes and models and is a non-invasive method for patients whose choice is not surgery. In this study, two types of Marland and ring with support are used. And the choice of pessary depends on the patient's examination. For grade 1 and 2 prolapse, a ring with support is used, and for grade 3 and 4 prolapse, a Marland . Sex is possible in two types of pessarys at the same time. The pessary is placed after the necessary training and filling out the questionnaire based on the patient's examination and 8 weeks later she returns again for control and re-examination.
Category
Treatment - Devices

2

Description
Control group: There are people who have uterine prolapse but for personal reasons do not want to have a pessary. These patients are given the necessary training on pessary and placement and no treatment is performed for them. vaginal examination is performed and the type of prolapse is recorded. The questionnaire is filled out by these patients at the first visit and patient follow-up is maintained by telephone at 4 weeks after placement and 8 weeks after placement.
Category
Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Taleghani hospital
Full name of responsible person
Dr. Soodabeh Darvish
Street address
Shahid Chamran Highway, Yemen St. Shahid Arabi St., Ayatollah Taleghani Hospital
City
Tehran
Province
Tehran
Postal code
1985711151
Phone
+98 21 2303 1111
Email
taleghani@sbmu.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
dr. Akbar Fotouhi
Street address
Tohid Square, Dr. Mirkhani St. (Eastern Nusrat)
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 8163 3685
Fax
+98 21 8163 3685
Email
afotouhi@tums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Dr. Maryam Modarres
Position
Associate Professor
Latest degree
Ph.D.
Other areas of specialty/work
Health Promotion
Street address
Tohid Square, Dr. Mirkhani St. (Eastern Nusrat)
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6105 4000
Email
ma_modars@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
sonia biglari gounbad
Position
student
Latest degree
Bachelor
Other areas of specialty/work
Midwifery
Street address
Tohid Square, Dr. Mirkhani St. (Eastern Nusrat)
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6105 4000
Fax
Email
biglari.sonia1@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
sonia biglari gounbad
Position
student
Latest degree
Bachelor
Other areas of specialty/work
Midwifery
Street address
Tohid Square, Dr. Mirkhani St. (Eastern Nusrat)
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6105 4000
Email
biglari.sonia1@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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