Evaluation of audio-visual integration and recalibration of auditory space in unilateral hearing loss pre and post auditory localization training using ventriloquism effect
Evaluation of the effects of Localization training on the of adaptation and recalibration of auditory spatial perception and its effects on the Ventriloquism Effect (VE) and the Ventriloquism After Effect VAE
Design
Clinical trial with a control group, the study will be performed on 50 subjects
Settings and conduct
Samples are selected from people referring to the audiology department of the Faculty of Rehabilitation Sciences. After grouping Based up on Inclusion criteria, initial evaluations are performed. Then the intervention is applied and then the tests are repeated.
Participants/Inclusion and exclusion criteria
Normal Group: Normal Hearing and Vision People
Lack of skill in music and being right hand
Experiment group: People with Unilateral Chronic Hearing loss
Lack of skill in music and being right hand and Normal Vision
Intervention groups
1- Experimental group are patients with chronic unilateral conductive hearing loss who receive localization training intervention. This intervention will improve the reduced auditory localization ability in this group and will ultimately improve the audio-visual integration.
2- The normal group also receives the intervention. To show the effect of the intervention in the experimental group, the normal group also receives the intervention. This intervention will improve the auditory localization performance and reduce its error. The end result will be an increase in audio-visual integration capabilities in this group
Main outcome variables
Basic localization Ability
Ventriloquism Effect
Ventriloquism After Effect
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20220206053952N1
Registration date:2022-04-11, 1401/01/22
Registration timing:prospective
Last update:2022-04-11, 1401/01/22
Update count:0
Registration date
2022-04-11, 1401/01/22
Registrant information
Name
Farnoush Jarollahi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 2225 0541
Email address
jarollahi.f@iums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-05-11, 1401/02/21
Expected recruitment end date
2022-10-23, 1401/08/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluation of audio-visual integration and recalibration of auditory space in unilateral hearing loss pre and post auditory localization training using ventriloquism effect
Public title
Evaluation of audio-visual integration in unilateral hearing loss
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Inclusion criteria in the norm group:
Normal hearing thresholds (based on goodman 1965)
Normal middle ear function
Absence of external ear l anomalies
No history of ear surgery
Not taking drugs that affect the CNS such as antiepileptic drugs and ...
Norm vision
Being right-handed
No history of professional activity in music
unilateral chronic hearing loss group:
Presence of conductive hearing loss in the right ear, with more than 30 dB HL
Hearing loss has lasted for at least 6 months
Absence of external ear l anomalies
Absence of cerumen and foreign body in the ear canal
No history of ear surgery
Not taking drugs that affect the CNS such as antiepileptic drugs and ...
Normal vision
Being right-handed
No history of professional activity in music
Exclusion criteria:
Reluctance to continue participating in the study at any stage
Age
From 18 years old to 40 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
50
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Other
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Research Ethics Committees of Iran University of Medical Sciences
Street address
Audiology department, School of Rehabilitation Sciences, Iran University of Medical Sciences Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
City
TEHRAN
Province
Tehran
Postal code
15459-13487
Approval date
2022-02-19, 1400/11/30
Ethics committee reference number
IR.IUMS.REC.1400.1077
Health conditions studied
1
Description of health condition studied
Poor Auditory Localization( Central )
ICD-10 code
H93.25
ICD-10 code description
Poor Auditory Localization( Central )
Primary outcomes
1
Description
Localization Improvement Ventriloquist Effect Improvement Ventriloquist After Effect Improvement
Timepoint
Before and after Intervention
Method of measurement
By Testing
Secondary outcomes
1
Description
Auditory Localization with BBN Stimui in 12 Azimoth Auditory Localization with Low/ High / BBN Stimuli in 5 Azim
Timepoint
Before and after intervention
Method of measurement
By testing
Intervention groups
1
Description
Intervention group 1 (People with unilateral chronic hearing loss) Each session is called a "learning unit". Each learning unit consists of 4 sections. In the first part, for ease of localization, the wide-band stimulus has a delay of 1000 milliseconds. On the other hand, four azimuths of 0, 90, 180 and 270 degrees are selected at this stage and the person under training is also told that the sound will be presented in one of these directions. This reduces the difficulty of locating and increases the patient's confidence to continue working. 5 stimuli will be provided from each speaker and the response will be recorded using the GUI. At this stage, the response of the patient is considered to be reinforced in such a way that, if it is correct, a green light on the response recorder will be turned on and feedback will be given. If the answer is wrong, a red light will come on first and then the correct answer will appear on the screen so that the patient can accurately identify the new symptoms. In the following, other azimuth will be presented diagonally. First Azimuth 30, 120, 210 and 300 degrees and next Azimuth 60, 150, 240 and 330 degrees in the mentioned style, the stimuli are presented and the answer related to each angle is recorded in the GUI, thus all 12 speakers Provide the stimulus and the person's response is recorded in 360 degrees.In the second part, all the previous steps are repeated using a stimulus with a delay of 300 milliseconds. In this new exercise, the positioning task becomes more difficult due to the reduction of the stimulus delay.At this stage, several corrective mechanisms have been considered to improve patients' performance. These mechanisms include the following: 1- Following the correct answer, the green light turns on for confirmation.2- After the wrong answer, the correct location of the speaker is displayed to increase the patient's accuracy 3- The angles that are answered incorrectly are identified and repeated in the next session 4- In angles where the wrong answer is not corrected, by limiting the patient's choices, it helps to increase his accuracy.In the third part, the task of localization becomes more difficult. In this way, the stimuli are presented randomly from the speakers and the listener has no background of the stimulus location and is no longer aware of the possible position of the sound source. In this section, the stimulus duration is 1000 milliseconds. Providing feedback and recording responses is the same as the previous step.In the fourth part, the details of the third part are applied, with the difference that the stimulus delay is 300 milliseconds. This will be the most difficult task for the patient.In total, there will be two weeks for each person and 3 days each week and one learning unit per day.After completing the four sections of the rehabilitation sessions, the patients' last response is recorded as "post-rehabilitation orientation response".
Category
Rehabilitation
2
Description
Intervention group 2: (People with normal hearing) All interventions to the intervention group 1 will be done here as well
Category
Rehabilitation
Recruitment centers
1
Recruitment center
Name of recruitment center
School of Rehabilitation Sciences, Audiology department
Full name of responsible person
Dr.Farnoush Jarollahi
Street address
Audiology Department, School of Rehabilitation Sciences, Iran University of Medical Sciences Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
City
Tehran
Province
Tehran
Postal code
15459-13487
Phone
+98 21 2225 0541
Email
jarollahi.f@iums.ac.ir
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
ِDR. Akram Pourbrbakht
Street address
Audiology department School of Rehabilitation Sciences, Iran University of Medical Sciences Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
City
Tehran
Province
Tehran
Postal code
15459-13487
Phone
+98 21 2225 0541
Email
Pourbakht.a@iums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?