Evaluation of therapeutic effect of topical semi-solid product containing sucralfate, zinc oxide, aloe Vera gel and peppermint essential oil and zinc oxide ointment in natural base containing Ghee oil and comparison with standard treatment containing zinc oxide in normal base in the process of healing and treatment of diaper rash: a pilot study And parallel

Evaluation of the effectiveness and effect of synergism including semi-solid containing sucralfate, zinc oxide, aloe vera gel and peppermint essential oil and animal oil

Clinical trial with control group, community-based and pragmatic, with parallel group, double-blind, randomized, design of 60 patients.

This study was performed on infants and children up to 24 months who suffered from diaper rash and referred to the office of Dr.Seighali located on Sattar Khan Street. zinc oxide, aloe vera gel powder, mint essential oil and the second group examines animal oil. According to similar pilot studies, the study population consists of 60 people, and each of The first and second experimental groups and 20 control groups. Patients participate in the study based on the physician's diagnosis of urinary incontinence and according to the patient's demographic information and parents consent, and are placed in one of the control or experimental groups. A pre-prepared informed consent form will also be provided to patients to become fully acquainted with the study process. The benefits of this study can be applied to children.

Inclusion criteria: doctors diagnosis of diaper rash, age range from birth to 24 months, Written consent and parental cooperation. Exclusion criteria: skin infection - fever- parental lake of cooperation.

Control group: includes 20 children with age range from birth to 24 months with diaper rash, who are treated for 7 days with our desired drug, which contains sucralfate, zinc, peppermint essential oil and aloe vera gel. Intervention group: The same as the control group, except that they are treated with a placebo that contains zinc.

comparison of the severity of burns, frequency of diaper changes and urination

Zu diesem Zweck werden 60 Umschläge (20 mit der ersten Arzneimittelkarte und 20 mit der zweiten Arzneimittelkarte und 20 mit der Placebokarte) vorbereitet. Umschläge sind mit Nummern von 1 bis 40 gekennzeichnet. Die Patienten werden nach dem Öffnen des versiegelten Umschlags einer von zwei Medikamenten- bzw. Placebogruppen, Nummer 1 bis 40, zugeordnet.

The patients, physicians, researcher and data collector (student) don’t know about who was receiving the placebo and who receiving a placebo. The informed consent was obtained from patients and they were informed that they could leave the trial at any time. The coding of the medicine boxes was done by a third party who was not involved in the study and at the end of the study, decryption took place. All tubes of the drug are the same in terms of design and color, while the cover of the prescribed tubes is coded.

All the data potentially can be shared after being unidentifiable.

Just after the articles publication.

For all investigators.

The person requesting the data should be a relevant expert in this field - All statistical analyzes performed can be provided - Information can be used by mentioning the name of the research and referencing the site to the research - Requirements: Mentioning the name of the research and codes Relevant research and all the required information as well as the name of the researcher and communication channels in case of receiving the required information.

Application can refer to the Department of Clinical Pharmacy, Faculty of pharmacy, Tehran Medical Science, Islamic Azad University, Dr. Hashemian or contact the researcher by sending email to shabanelahe@gmail.com or calling 09210907926.

Application can apply for research information by visiting the department or by contacting the e-mail address and telephone number as well as providing information on academic studies and the purpose of requesting the information. Applicant must commit themselves to mention the source. If the request is sent six months after the publication of research information the researcher will send the data to the requesting party by email within a week.