Protocol summary

Study aim
Comparison of influence of whitening and regular dentifrices on color stability of orthodontic clear ligatures in oral environment
Design
A randomized, double-blind, randomized controlled clinical trial was performed on 66 patients using the randomization tables available at www.stattrek.com.
Settings and conduct
Patients who are undergoing fixed orthodontic treatment at Ahwaz Dental School are selected at the end of the teeth alignment phase. After obtaining informed consent, Orthogonizers brand ligatures are used on the lower anterior teeth of all patients. Patients are randomly divided into three groups of 22 patients. Patients are asked to brush their teeth twice a day for 5 minutes each time using the toothpaste. Canon cameras are used to determine the primary color.All photos are taken in the same environment and light. It is then placed in the mouth for 4 weeks and the patient brushes the ligatures using the appropriate toothpaste and is removed after this period. Then the samples are photographed again and all the photos ( Both primary and post-oral photographs are examined to determine the color of the ligatures using Photoshop 2019 software to evaluate the L, a, and b parameters.
Participants/Inclusion and exclusion criteria
The patient is willing to participate in the study, Have a good level of oral health, 4 lower anterior teeth are aligned and without diastema, Do not use any mouthwash, medication, tobacco or special diet, Absence of systemic diseases ؛ Patient non-cooperation
Intervention groups
The first group uses Arm & Hammer Advance White Extreme toothpaste, the second group uses Crest Complete Extra Whitening toothpaste and the third group uses regular Crest Cavity Protection toothpaste.
Main outcome variables
The effectiveness of Arm & Hammer Advance White, Crest Complete Extra Whitening and Crest Cavity Protection toothpaste on color stability of the elastic ligature

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20220315054292N1
Registration date: 2022-03-28, 1401/01/08
Registration timing: prospective

Last update: 2022-03-28, 1401/01/08
Update count: 0
Registration date
2022-03-28, 1401/01/08
Registrant information
Name
Majid Aryannejad
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 61 3376 5825
Email address
aryannejad.m@ajums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-04-21, 1401/02/01
Expected recruitment end date
2022-12-21, 1401/09/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Influence of whitening and regular dentifrices on color stability of orthodontic clear ligatures in oral environment
Public title
Influence of whitening and regular dentifrices on color stability of orthodontic clear ligatures
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
The patient is willing to participate in the study Have a good level of oral health 4 lower anterior teeth are aligned and without diastema Do not use any mouthwash, medication, tobacco or special diet Absence of systemic diseases
Exclusion criteria:
Patient non-cooperation
Age
From 15 years old to 25 years old
Gender
Both
Phase
3
Groups that have been masked
  • Participant
  • Care provider
  • Outcome assessor
  • Data analyser
Sample size
Target sample size: 66
Randomization (investigator's opinion)
Randomized
Randomization description
Using random tables available at www.stattrek.com, they are selected by simple individual randomization.
Blinding (investigator's opinion)
Double blinded
Blinding description
Using tubes that do not have the specifications of the relevant toothpaste on them and the tubes are named by the researcher.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Ahvaz Jundishapur University of Medical Sciences
Street address
Ground Floor, Ahvaz Jundishapur University of Medical Sciences and Health Services, Vice Chancellor for Research and Technology, University City, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
1579461357
Approval date
2022-03-12, 1400/12/21
Ethics committee reference number
IR.AJUMS.REC.1400.698

Health conditions studied

1

Description of health condition studied
Influence of whitening and regular dentifrices on color stability of orthodontic clear ligatures
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
The amount of discoloration of clear orthodontic ligatures
Timepoint
Record the primary color of the ligatures , 28
Method of measurement
The samples are photographed and all photos (both initial and post-oral photos) to determine the color of the ligatures using Photoshop software version 4. 0. 20 (Adobe Photo Shop cc 2019) for evaluation Parameters L, a, b are checked.

Secondary outcomes

empty

Intervention groups

1

Description
first Intervention group: Arm & Hammer Advance White Extreme Whitening Toothpaste , Second Intervention group: Crest Complete Extra Whitening toothpaste
Category
Diagnosis

2

Description
Control group: Crest Toothpaste Cavity Protection Regular
Category
Diagnosis

Recruitment centers

1

Recruitment center
Name of recruitment center
Ahvaz Jundishapur Dental School
Full name of responsible person
Marzieh mazhari
Street address
Jundishapur Dental School, Dey Ave, Golestan Blvd, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
6135715775
Phone
+98 61 3360 7544
Email
Marzie.mazhari@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Marzieh Mazhari
Street address
Dental School, Ahvaz Jundishapur University Of Medical Sciences, Golestan Blvd, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
6135715775
Phone
+98 61 3320 5168
Email
Marzie.mazhari@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ahvaz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Majid Aryannejad
Position
Student
Latest degree
A Level or less
Other areas of specialty/work
Dentistry
Street address
Jundishapur Dental School, West Dey Ave, Golestan Blvd, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
6135715775
Phone
+98 61 3376 5825
Fax
Email
aryannejad.m@ajums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Marzieh Mazhari
Position
Assistant professor
Latest degree
Specialist
Other areas of specialty/work
Orthodontics
Street address
Dental school, Ahvaz Jundishapur University Of Medical Sciences, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
6135715775
Phone
+98 61 3360 7544
Email
Marzie.mazhari@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Majid Aryannejad
Position
Student
Latest degree
A Level or less
Other areas of specialty/work
Dentistry
Street address
Jundishapur Dental School, West Dey Ave, Golestan Blvd, Ahvaz
City
Ahvaz
Province
Khouzestan
Postal code
6135715775
Phone
+98 61 3376 5825
Fax
Email
aryannejad.m@ajums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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