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Study aim
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This study was designed to investigate the effect of intracuff local anesthetics on emerging reactions after general anesthesia.
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Design
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Clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 350 patients. Random card selection method is used for randomization.
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Settings and conduct
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In the operating room of Imam Hossein (AS) Hospital in Tehran, before performing anesthesia, an anesthesia technician, without informing the anesthesiologist and the patient, uses a random selection of a card to identify the patient group and one of the syringes containing one of the drugs in each group. Submits to the anesthesiologist and records this information separately. At the end of the surgery, the questionnaire is delivered to the first technician. Information outside the operating room is tracked by the same anesthesiologist.
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Participants/Inclusion and exclusion criteria
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All patients over 18 years of age with physical condition I or II of the American Society of Anesthesiologists (ASA) who undergo elective limb surgery under general anesthesia for one to three hours by endotracheal intubation in a supine position are included in the study. To be. Patients with a history of sore throat, hoarseness or cough, moderate to severe illness, recent respiratory infection, history of airway prolapse, long history of intubation, smokers and illicit drug users, difficult to predict intubation, risk of aspiration Stomach contents, history of tracheal or laryngeal surgery, BMI> 30.0, use of a nasogastric tube or nasal or oral airway will be excluded.
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Intervention groups
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After endotracheal intubation, the endotracheal tube cuff will be filled in one of the following ways: air, isotonic saline, ropevacaine, bupivacaine, lidocaine.
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Main outcome variables
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Cough; Sore throat; bucking on the endotracheal tube