Comparison of the effect of Achillea Cretica herbal treatment with Dinogest on the pain and size of endometriosis lesions in patients referred to Arash Hospital.

Comparison of the effect of herbal medicine treatment with Achillea Cretica and Dinogest on pain and size of endometrial lesions in patients with endometriosis.

The clinical trial has an intervention and control group, with parallel, double-blind, randomized groups based on 4-size two-allele random number blocks, phase 3, on at least 70 patients.

The patient is unaware of the type of treatment received. The final results of the study will be reviewed by a physician who is unaware of the type of intervention. For statistical analysis, a statistician who does not know how to assign individuals to groups is used. The random assignment list of patients is only at the disposal of the clinic secretary. When the physician declares a patient eligible, the clinic secretary provides the envelope to the physician and the treatment is performed according to the type mentioned in the envelope.

Inclusion criteria: Women aged 18 to 45 years with pain associated with endometriosis. Exclusion criteria include pregnancy or lactation, amenorrhea within 3 months prior to enrollment, need for endometriosis surgery, previous use of hormonal agents, abnormal findings on gynecological examination, risk factors for decreased bone density

Patients referred to the laparoscopic clinic of Arsh Hospital who are eligible to enter, if admitted with satisfaction. They are divided into two groups using the randomization block method. The first group receives 2 grams of Dinogest tablets daily for 3 months with rice syrup and the second group receives 2 grams of Dinogest tablets daily with placebo syrup for 3 months.

Evaluation of dysmenorrhea, dyspareunia, pelvic pain, and change in size and number of endometriosis lesions in patients

Our sample size is 80 people, with 40 people in each group. We will use the block randomization method by using: www.sealedenvelope.com. The number of blocks considered is 4.

The random assignment list of patients is only available to the clinic secretary. To hide the random allocation process, the treatment sequence card is written in order, then the cards will be placed in sealed envelopes. On each envelope, a random 10-digit code is written without order and frame, which is the relevant patient identification number, and only the design methodologist will be aware of the relevant code. When the doctor announces that a patient is eligible, the clinic secretary provides the envelope to the physician and the desired treatment is performed according to the type mentioned in the envelope Patients do not know the type of syrup they receive and one group is given a placebo and the other group is given medicine. The final results of the study will be reviewed by a physician who is unaware of the type of intervention. For statistical analysis, a statistician who does not know how to assign individuals to groups is used.