The effect of Action Observation therapy (AOT) on balance and kinematic parameters of gait in patients with multiple sclerosis.

Evaluation of the effect of Action Observation on Balance and kinematic parameters of gait using a gait analysis system in patients with Multiple Sclerosis (MS)

A clinical trial with parallel groups including an action observation group and a control group, single-blind, randomized on 24 patients with MS.

MS patients will be included in the study if they qualify and will be randomly assigned to an intervention or control group. This study will be conducted under single-blind conditions. The assessor and therapist that assess and provide routine rehabilitation, evaluate and treat patients in separate rooms based on the assumption that each patient has undergone action observation therapy.

MS patients who have an EDSS score between 3 and 6, an MMSE score of more than 24, age between 18 to 45 years will be included in the study. recurrence of the disease 3 months before the intervention, pregnancy, and breastfeeding, inability to sit without support, inability to stand for at least 10 seconds with support, Other orthopedic and neurologic diseases will be excluded.

The intervention group watched a 15-minute video from different angles containing exercises commonly used to improve walking in people with MS and then performed the same exercises with the help of an experienced therapist. The control group will watch a 15-minute video containing a video depicting landscapes and then perform the same exercises as the intervention group under the same conditions. The interventions will last three sessions a week for 6 weeks.

The velocity of the center of pressure; Length, width, and time of step; Stride length and time; stance time; swing time; walking speed; cadence; Kinematics of the pelvis, hip, knee, and ankle joints

A simple randomization method will be used to assign people into two groups, which will be done by selecting numbered papers (1-24) that are inside sealed envelopes, and patients will be assigned to intervention and control groups. The patient will choose one of the envelopes, even numbers are assigned to the intervention group and odd numbers to the control group. Then the selected envelope will be removed and this procedure will be repeated for the next patient.

The study was designed as a single-blinded study. In this intervention, the health care personnel or the clinical caregiver and the person who is in charge of the evaluation are kept blind. Before the trial started, participants were randomly divided into two groups, and other researchers were unaware of the distribution of patients. The clinical caregiver provides routine rehabilitation in the therapeutic exercise room, separate from the place where the activity observation intervention is offered, assuming that all participants will be subjected to the new intervention. Participants are asked not to discuss the movie they saw with the clinical caregiver. In addition, the evaluator evaluates the participants in a separate laboratory presuming all patients will undergo observation. We ask patients not to discuss the film they have seen with the evaluator. The evaluator and clinical supervisor are unaware of what is happening in the new intervention room as the leading researcher presents videos in a separate room.

All the data of this study can be shared after de-identifying the participants.

The data of this study will be accessible three months after the results are published.

Researchers from academic and scientific institutions will have access to this study's data

Using this study does not require any special conditions.

To receive data and documents, please refer to Dr. Abolqasem Fallahzadeh, Professor of Shiraz Rehabilitation Faculty. Phone: 07136271551 E-mail: A_Fallahzadeh@Sums.ac.ir Address: Shiraz Faculty of Rehabilitation Sciences, 1 Abivardi Street, Chamran Blvd.

A letter of request is enough to receive data.