Protocol summary

Study aim
evaluating the effect of reducing preoperative clear fluid fasting time on hemodynamic statue of a child before and after operation and evaluating the risk of pulmonary aspiration in 2 to 6 years old children
Design
clinical trial has a control group with a parallel group without blinding the research will be performed on 96 patients .excel will be used for randomization
Settings and conduct
96 patients enter the study after and are divided into case and control groups. Complete collection and examination is performed. Parents will be given a full explanation on how to keep children fasting. With the cooperation of surgeons and anesthesiologists, in Tabriz shohada hospital,the day before the operation, the parents will be explained that one hour before the operation, with the help of a nurse, 4ml / Kg of plain water will be given to the child. Patients will not receive intravenous fluids before surgery. When entering the operating room hemodynamic status, nausea and vomiting during induction or awakening of the patient and the appearance of any signs of aspiration will be recorded in the recovery phase and chest x-ray in case of signs of signs Will be obtained for pulmonary aspiration.
Participants/Inclusion and exclusion criteria
Including criteria 1.Children between 2-6 years old 2.Time of operation under 2 hours 3.Obtaining parents' satisfaction Excluding criteria 1.age below 2 years and over 6 years 2.parental dissatisfaction 3.operations over 2 hours 4.operations of gastrointestinal tract 5.history of special medications 6.history of a previous surgery 7.history of congenital anomalies 8.patients who undergo emergent surgeries
Intervention groups
Patients will receive 4ml/kg clear fluids one hour before entering operation room.Routin fasting time will be used in control group.
Main outcome variables
Signs of pulmonary aspiration;hemodynamic statue

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20220611055132N1
Registration date: 2023-11-29, 1402/09/08
Registration timing: prospective

Last update: 2023-11-29, 1402/09/08
Update count: 0
Registration date
2023-11-29, 1402/09/08
Registrant information
Name
Maryam Hejazi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 41 3386 1075
Email address
hejazimaryam28@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-12-06, 1402/09/15
Expected recruitment end date
2024-02-04, 1402/11/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluating the effect of reducing preoperative clear fluid fasting time on hemodynamic status and risk of aspiration in 2-6 years old children
Public title
The effect of reduced clear fluid fasting time on hemodynamic status and risk of pulmonary aspiration in children
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Children between 2-6 years old Time of operation under 2hours Obtaining parents' consent
Exclusion criteria:
age below 2 years and over 6 years parental dissatisfaction operations over 2 hours operations of gastrointestinal tract history of special medications history of a previous surgery history of congenital anomalies patients who undergo emergent surgeries
Age
From 2 years old to 6 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 96
Randomization (investigator's opinion)
Randomized
Randomization description
Using a Computerized randomization with block diagram the studied patients will be divided into interventional group and control group to reduce bias.The block randomization method is designed to randomize subjects into groups that result in equal sample sizes. This method is used to ensure a balance in sample size across groups over time.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Tabriz University of medical science
Street address
Tabriz,Golshahr,Golha blvd,Omidfar alley,No.25,4th floor
City
Tabriz
Province
East Azarbaijan
Postal code
5167856961
Approval date
2023-10-23, 1402/08/01
Ethics committee reference number
IR.TBZMED.REC.1402.529

Health conditions studied

1

Description of health condition studied
In this study disease is not examined
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Hemodynamic statue
Timepoint
Preoperative-during surgery-post operative
Method of measurement
Non invasive monitoring of vital signs

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group:They will receive 4ml/kg clear fluids(water) one hour before surgical operation
Category
Other

2

Description
Control group:The patients of Control group will receive regular fasting regime
Category
Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Shohada hospital
Full name of responsible person
Dr Naghi Abedini
Street address
Anesthesia Department -Second Flour-Medical College-Tabriz University of Medical Science-Golgasht St-Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 1994
Email
Naghi26@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Parviz Shahabi
Street address
3rd Floor-No 2 Central Building-Tabriz University of Medical Science-University St-Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5165665931
Phone
+98 41 3335 7310
Email
parvizshahabi@gmail.com
Grant name
0
Grant code / Reference number
0
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tabriz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Naghi Abedini
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
Anesthesia Department-Second Flour-Medical College-Tabriz University of Medical Science-Golgasht St-Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 1994
Email
Naghi26@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Naghi Abedini
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
Anesthesia Department-2th floor-Medical College-Tabriz university of Medical science-Golgasht St-Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 1994
Email
Naghi26@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Naghi Abedini
Position
Associate Professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
Anesthesia Department-Second Flour-Medical College-Tabriz University of Medical Science-Golgasht St-Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 914 313 8038
Email
Naghi26@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
0
When the data will become available and for how long
0
To whom data/document is available
0
Under which criteria data/document could be used
0
From where data/document is obtainable
0
What processes are involved for a request to access data/document
8
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