Investigation of the Honey and the Trigonella foenum-graceum L (fenugreek) ‎seeds product effect on chronic obstructive pulmonary Disease: Double – Blinded ‎Trial‏ ‏

Evaluation of the effect of honey and fenugreek seed product in the recovery and control of clinical symptoms (cough, sputum, shortness of breath) in patients with chronic obstructive pulmonary disease.  Evaluation of the effect of honey and fenugreek seed product on pulmonary function tests (spirometry) in patients with chronic obstructive pulmonary disease.

The clinical trial work has a control group, with parallel, double-blind, randomized groups on 81 patients, and the type of treatment is allocated to patients in a simple random manner with the help of power G software. ,

After the homogenization of the groups in terms of intervening factors, the manufactured drugs including: honey syrup and fenugreek seeds, honey syrup and placebo will be coded. One group will receive honey syrup, the next group will receive a combination of fenugreek and honey, and the third group will receive a placebo. For the double-blindness of the study, the doctor, student, and patient will not know about the coding. And the codes are kept with the analyzer and the code given to each patient will be recorded on the patient information registration form

Patients are randomly selected from those who refer to Tabriz University of Medical Sciences (campus clinic) by a lung specialist with a diagnosis of COPD, who have stable conditions and do not have underlying diseases, age range 30 to 60 years.

Patients will be divided into three groups of 27 people and one group will receive placebo as a control group, the second group will receive honey syrup and the third group will receive a combination of honey and fenugreek products for 4 weeks.

Cough confusion Activity shortness of breathg Spirometry

ُSimple randomizationDue to the double-blindness of the study, the doctor, student, and patient will not know about the coding. And the codes are kept with the analyzer and the code given to each patient will be recorded on the patient information registration for

Direction of Double blind study، doctor medical، student and patient dont know of cods.

All data cannot be shared after de-identifying individuals, but part of the information related to the main outcome can be shared

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