Multiple sclerosis (MS) is a chronic, progressive neurological disease that results in a set of environmental factors, genetic and autoimmune occurs. This study investigated the effect of acupressure in reducing fatigue and pain that patients with MS. METHODS: A sample of 100 women (18-40 years) of the MS Society in Tehran have inclusion criteria (female, they have a week of pain, fatigue are mentioned, the use of lack of acupressure) are selected. Patients randomized in the acupressure group (n = 50) and controls (n = 50). Pain is measured with visual analog scale and fatigue is measured with FSS questionnaire.Interventions in this study is to educate patients for intervention.In groups of three points LI4, SP6, ST36, each for two minutes on each side of the body three times a day for two weeks to do by themselves. In control group instead of just pushing the points they are touched.The FSS questionnaire and visual analog scale of pain completed once before the first intervention, immediately after the intervention, two weeks and four weeks after they completed the intervention. Patients who do not want to do and don't a quarter days are excluded.
General information
Acronym
multiple sclerosis(MS)
IRCT registration information
IRCT registration number:IRCT201108276247N2
Registration date:2011-08-29, 1390/06/07
Registration timing:prospective
Last update:
Update count:0
Registration date
2011-08-29, 1390/06/07
Registrant information
Name
Farideh Bastani
Name of organization / entity
Tehran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 8857 2278
Email address
f-bastani@sina.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Nursing Research Center, Tehran University of Medical Sciences
Expected recruitment start date
2011-09-01, 1390/06/10
Expected recruitment end date
2011-12-01, 1390/09/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of acupressure on severity of fatigue and pain of multiple sclerosis patients.
Public title
The Effect of Acupressure on Severity of Fatigue and Pain of Multiple Sclerosis (MS) disease in female members of MS Association.
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: women with stable vital signs; lack of wounds and deformity in the LI4( When the thumb is in full extension, the middle point of the angle between the first and second metacarpal), ST36(The width of a finger tip to the side with the lower edge of the tibia 3 cun below the knee), SP6(or sanyingiao 3 cun above the inner ankle to the back edge of the posterior tibia); being able to read and write; confirmed fatigue related to MS; no history of using acupressure; no history of smoking, using drugs or pills; age between18-40 and EDSS is between 0-5.5.
Exclusion criteria: unwillingness to continue participation in the trial; complications during the procedure; known physical and mental disorders; being perform the acupressure point 4LI, ST36, SP6 and don't have any sense of warmth, heaviness, swelling or numbness and not performing more than a quarter of days.
Age
From 18 years old to 40 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
100
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Tehran University of Medical Sciences
Street address
Tehran University of Medical Sciences, Ghods St., Keshavarz Blvd.
City
Tehran
Postal code
Approval date
2011-07-25, 1390/05/03
Ethics committee reference number
13783
Health conditions studied
1
Description of health condition studied
multiple sclerosis
ICD-10 code
G35
ICD-10 code description
multiple sclerosis
Primary outcomes
1
Description
Pain reduction
Timepoint
Before the intervention, immediately after, two weeks after the first two weeks after the last intervention
Method of measurement
Visual analog scale
2
Description
Fatigue reduction
Timepoint
Before the intervention, immediately after, two weeks after the first two weeks after the last intervention
Method of measurement
Fatigue Severity Scale
Secondary outcomes
1
Description
Severity of pain
Timepoint
Before the intervention, immediately after, two weeks after the intervention and four weeks after the first intervention
Method of measurement
Visual analog scale
2
Description
Severity of fatigue
Timepoint
Before the intervention, immediately after, two weeks after the intervention and four weeks after the first intervention
Method of measurement
Fatigue Severity Scale
Intervention groups
1
Description
Patients in the intervention group or individual instruction for acupressure points (LI4, SP6, ST36) for two minutes on each side, three times a day for two weeks
Category
Treatment - Other
2
Description
Control group: same the intervention group rather than just do the palpation.