An assessment effect of low tidal volume ventilation in on-pump Coronary artery bypass graft surgery on post-operative pulmonary complications.

Determining the effect of mechanical ventilation with low volume and number during cardiopulmonary pump in heart surgery with the occurrence of pulmonary, renal and liver complications after surgery.

Clinical trial with control group, with parallel groups, double-blind, randomized, 60 participants

This study was conducted in Baqiyatullah Hospital with the aim of determining the effect of mechanical ventilation with low volume and number during cardiopulmonary pump in heart surgery with the occurrence of pulmonary, renal and liver complications after surgery.

Inclusion criteria: 1. Not a candidate for emergency surgeries 2. No history of open heart surgery 3. Not suffering from known liver, kidney and lung disease. Exclusion criteria: 1. Bleeding after surgery 2. The need for re-surgery for any reason

After obtaining informed consent from ASA class 1 and 2 CABG candidates, 60 patients were randomly divided into two intervention and control groups of 30. After establishing standard monitoring and IBP and CVP, induction of anesthesia will be done with the same method in patients of both groups. After placing the patient under CPB, patients in the intervention group receive ventilation with a tidal volume (3-4 ml/kg) and a number of 6-8 breaths/minute. Control group doesn't receive any ventilation according to the hospital routine after undergoing CPB. Renal and hepatic parameters are recorded before surgery and on the first, second and third days after surgery. vital signs, duration of mechanical ventilation in ICU-OH, duration of hospitalization in ICU are recorded.

Evaluation of pulmonary, renal and hepatic complications after surgery, Evaluation of length of stay in the ICU, Evaluation of hospital costs, Evaluation of patients' satisfaction and quality of life

After obtaining informed consent from ASA class 1 and 2 CABG candidates, 60 patients were randomly divided into two intervention and control groups of 30. Participants were not aware of their group.

After obtaining informed consent from ASA class 1 and 2 CABG candidates, 60 patients were randomly divided into two intervention and control groups of 30. After establishing standard monitoring and IBP and CVP, induction of anesthesia will be done with the same method in patients of both groups. After placing the patient under CPB, patients in the intervention group receive ventilation with a tidal volume (3-4 ml/kg) and a number of 6 to 8 breaths per minute. Patients in the control group do not receive any ventilation according to the hospital routine after undergoing CPB. Kidney (BUN, Cr) and liver (SGOT, SGPT, ALKP) parameters are recorded before surgery and on the first, second and third days after surgery. In addition to laboratory parameters, vital signs, duration of mechanical ventilation in ICU-OH, duration of hospitalization in ICU are recorded by a person who does not know the exposure status of patients. The outcome registrar was not aware of the patient group. After collecting and recording data, they are analyzed using SPSS statistical software.