Protocol summary

Study aim
Comparison between acupuncture with Laser and acupuncture with acupressure on pain and function of patients with knee osteoarthritis.
Design
A clinical trial without a control group with three treatment groups, one-sided blind on 36 patients
Settings and conduct
Patients referred to the physiotherapy clinic of Shahid Beheshti Rehabilitation Faculty and Hakim physiotherapy clinic with matching Three groups of acupuncture treatment. Combination with laser acupuncture points and combination with acupressure blinding the therapist with a separate primary evaluator
Participants/Inclusion and exclusion criteria
Adults aged 40 to 75 years with grade 2 or 3 knee osteoarthritis based on the Kellgren Lawrence criteria, referring to the physiotherapy clinic of Shahid Beheshti Rehabilitation Faculty and Hakim Physiotherapy Clinic • Target population: eligible patients described to enter the study Main entry and exit conditions: Age 40 to 75 years Chronic one-sided knee pain that has lasted for more than 6 months Diagnosis of grade 2 or 3 osteoarthritis BMI: 18.5-29.9 Pain as much as 40 to 90% of the total VAS score Having no contraindications to acupuncture Signs of severe chronic diseases and history of knee surgery, as well as signs of physical therapy in the past six months Absence of patellofemoral joint osteoarthritis
Intervention groups
They are divided into three treatment groups: "acupuncture", "acupuncture and laser acupuncture points" and "acupuncture and acupressure".
Main outcome variables
Primary outcome:Pain level/ Secondary outcomes:The level of physical ability in terms of performance,Movement range of active flexion of the knee,Movement range of active knee extension

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20221117056531N1
Registration date: 2022-12-20, 1401/09/29
Registration timing: prospective

Last update: 2022-12-20, 1401/09/29
Update count: 0
Registration date
2022-12-20, 1401/09/29
Registrant information
Name
Aida Zolghadr
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 6632 5502
Email address
aidazolghadr@sbmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-12-22, 1401/10/01
Expected recruitment end date
2023-05-21, 1402/02/31
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison between acupuncture with Laser and acupuncture with acupressure on pain and function of patients with knee osteoarthritis.
Public title
Comparison between acupuncture with Laser and acupuncture with acupressure on pain and function of patients with knee arthrosis.
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Age 40 to 75 years Chronic one-sided knee pain that has been going on for more than 6 months (33) Diagnosis of grade 2 or 3 osteoarthritis with radiology according to the Kellgren-Lawrence scale (33) diagnosed by the evaluating therapist BMI: 18.5-29.9 The amount of pain as much as 40 to 90% of the total VAS score6.
Exclusion criteria:
Having contraindications for acupuncture (including infection and open wound or cancer) (20) Suffering from other chronic diseases in the critical phase 3. Intra-articular injection, use of knee support, surgery or use of drugs that affect treatment and evaluation. history of joint injections to reduce pain in the past 30 days or the intention to do so during the study (20), attendance during pregnancy and breastfeeding (30) history of performing single or combined treatments or physiotherapy in the last 6 months (17) Having a pacemaker and taking anticoagulant drugs (17) and uncontrolled blood pressure history of surgery in the considered knee (20) radiographic evidence of severe osteoarthritis in the patellofemoral joint
Age
From 40 years old to 75 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Investigator
Sample size
Target sample size: 36
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
In this study, the researcher who conducts the intervention is blinded, and the allocation of people into three groups and the registration of their characteristics will be done by another person.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Shahid Beheshti University of Medical Sciences
Street address
Rajaee St
City
تهران
Province
Tehran
Postal code
1373885693
Approval date
2022-11-16, 1401/08/25
Ethics committee reference number
IR.SBMU.RETECH.REC.1401.506

Health conditions studied

1

Description of health condition studied
knee mosteoarthritis
ICD-10 code
M00-M99
ICD-10 code description
اختلال ماهیچه ای استخوانی= آرتروز زانو

Primary outcomes

1

Description
Pain intensity according to VAS
Timepoint
Baseline - first session - sixth session - after three weeks
Method of measurement
Visual Analogue Scale

Secondary outcomes

1

Description
Performance change
Timepoint
Baseline - session one - session six - three weeks later
Method of measurement
Western Ontario and McMaster Universities Osteoarthritis Index Total score

2

Description
changing the range of motion of Aktiochum and opening the knee
Timepoint
Baseline - session one - session six - three weeks later
Method of measurement
By goniometer

Intervention groups

1

Description
First intervention group: Acupuncture - In this group, during six treatment sessions, first 15 minutes of IR rays and then 5 points of acupuncture XI YAN-SP9-GB34-ST35-ST36 are performed for twenty minutes. Eco needle is used in size 2.5 cm long and 0.25 mm in diameter.
Category
Rehabilitation

2

Description
Intervention group 2: Acupuncture and laser acupuncture points - In this group, during six treatment sessions, first 15 minutes of IR rays are received. Then, for 20 minutes, acupuncture points XI YAN-SP9-GB34-ST35-ST36 are subjected to acupuncture with echo needles of 25 mm size and 0.25 mm diameter. Then laser the same points for 5 minutes with MODE parameters; PULSED- PEAK POWER; 150 mW- AVERAGE POWER: 100 mW- DOSE 6 J PER POINT- NUMBER OF POINT 5 is performed with 870M laser of Novin company
Category
Rehabilitation

3

Description
Intervention group 3: Acupuncture and acupressure - in this group, during six treatment sessions, first 15 minutes of IR rays are received. Then, for 20 minutes, acupuncture points XI YAN-SP9-GB34-ST35-ST36 are subjected to acupuncture with echo needles of size 25 mm and 0.25 mm in diameter. Then, for 7 minutes, acupressure on the same points with thumb pressure Therapist's hand is performed for 80 seconds to create a sensation. Then the patient performs active knee movements for 5 minutes
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Beheshti Rehabilitation Faculty Physiotherapy Clinic
Full name of responsible person
parsa salemi
Street address
damavand st
City
تهران
Province
Tehran
Postal code
1616913111
Phone
+98 21 7754 8496
Email
tavan2020@yahoo.com

2

Recruitment center
Name of recruitment center
Hakim Physiotherapy Clinic
Full name of responsible person
Mojtaba ghala shihini
Street address
aghaei
City
tehran
Province
Tehran
Postal code
1373885691
Phone
+98 912 340 4225
Email
aidazolghadr.ot@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Dr. Afshin Zarghi
Street address
velenjak- 7th floor- bldg no 2- SBMUS- ARABI AVE
City
tehran
Province
Tehran
Postal code
1985717443
Phone
+98 21 23871
Email
info@sbmu.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
aida zolghadr
Position
student
Latest degree
Bachelor
Other areas of specialty/work
Physiotherapy
Street address
rajaei
City
tehran
Province
Tehran
Postal code
1373885693
Phone
+98 21 6632 5502
Email
aidazolghadr.pt@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Aida zolghadr
Position
student
Latest degree
Bachelor
Other areas of specialty/work
Physiotherapy
Street address
rajaei
City
tehran
Province
Tehran
Postal code
1373885693
Phone
+98 21 6632 5502
Email
aidazolghadr.pt@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Aida zolghadr
Position
student
Latest degree
Bachelor
Other areas of specialty/work
Physiotherapy
Street address
rajaei
City
tehran
Province
Tehran
Postal code
1373885693
Phone
+98 21 6632 5502
Email
aidazolghadr.pt@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
Part of primary and secondary outcome data
When the data will become available and for how long
The access period starts 6 months after the results are published
To whom data/document is available
Industrial and academic researchers
Under which criteria data/document could be used
Personal use of documents is not allowed
From where data/document is obtainable
aidazolghadr.pt@gmail.com email
What processes are involved for a request to access data/document
Send a request to an email address and receive an initial response. Then sending the information by the researcher until one week later
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