Protocol summary

Study aim
Comparing the effects of using knee immobilizer and skin traction in pain management in patients with peritrochanteric fractures
Design
This study will be a three-arm, parallel-group, nonblinded, randomized, active-controlled trial.
Settings and conduct
A total of 75 patients with peritrochantric fracture in the orthopedic ward of the Imam Hossein will randomly be divided into three groups. Patients in the treatment groups will receive the study interventions, including knee immobilizer or skin traction, and in the control group will receive the standard analgesia protocol without any additional intervention. No blinding will be performed in this study.
Participants/Inclusion and exclusion criteria
Patients aged 40 to 70 who have peritrochanteric fractures and are aware of their pain level will be included in this study. Exclusion criteria are patients with multiple trauma or concurrent fractures and hepatic or renal dysfuntion.
Intervention groups
In this study, patients will be randomly divided into three groups, including skin traction, knee immobilizer, and control. The two intervention groups including the skin traction and knee immobilizer ones will receive the interventions during the preoperative course and patient hospitalization. The control group will receive no additional intervention for pain management except for the standard analgesia protocol.
Main outcome variables
The visual analog scale (VAS, 0-10) for pain at rest.

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20221226056923N1
Registration date: 2023-06-03, 1402/03/13
Registration timing: prospective

Last update: 2023-06-03, 1402/03/13
Update count: 0
Registration date
2023-06-03, 1402/03/13
Registrant information
Name
Farzad Amouzadeh
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 7343 3000
Email address
f.amouzadeh@sbmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-06-22, 1402/04/01
Expected recruitment end date
2024-02-20, 1402/12/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of the effects of knee immobilizer and skin traction in pain management of patients with peri-trochanteric fracture
Public title
Analgesic effect of knee immobilizer and skin traction in pertrochantric fracture
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Age between 40 and 70 patients with peri-trochantric fractures Patients who are neurologically oriented and aware of their pain
Exclusion criteria:
Patients who have multiple trauma or those with fractures in other bones Obesity (BMI > 35) Patients with renal and/or hepatic disorders Patients who are diagnosed with Myasthenia Gravis, Dermatitis or have delusions Opium addict patients
Age
From 40 years old to 70 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 75
Randomization (investigator's opinion)
Randomized
Randomization description
Patients will be randomly assigned into three groups using block randomization. For randomization, no stratification will be performed. For block randomization “R” version 3.6.3 (R Foundation for Statistical Computing, Vienna, Austria), RStudio, and "blockrand" package will be used (randomization tool will be statistical computer software). For allocation concealment, sealed opaque envelops will be used.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Shahid Beheshti University of Medical Sciences
Street address
7th Floor, Building Number 2, Shahid Beheshti University of Medical Sciences, Arabi Avenue, Daneshjoo Boulevard, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1989934148
Approval date
2022-08-14, 1401/05/23
Ethics committee reference number
IR.SBMU.RETECH.REC.1401.337

Health conditions studied

1

Description of health condition studied
Pertrochanteric fracture of femur
ICD-10 code
S72.1
ICD-10 code description
Pertrochanteric fracture

Primary outcomes

1

Description
Visual analog scale (VAS) for pain at rest
Timepoint
0, 12, AND 24 h after the hospitalization and daily afterward up to the time of operation
Method of measurement
Visual analog scale

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group 1: In the intervention group 1, patients will receive the study intervention, including the knee immobilizer during their hospitalization and before the operation. Knee immobilizer is a removable device that maintains the stability of the knee. In addition, patients will receive the standard protocol for the preoperative analgesia. The standard protocol will be IV acetaminophen (Apotel) 1 g every 12 h and IV morphine sulfate 5 g as needed.
Category
Treatment - Devices

2

Description
Intervention group 2: In the intervention group 2, patients will receive the study intervention, including the skin traction during their hospitalization and before the operation. Traction is a directional pull on an extremity. In addition, patients will receive the standard protocol for the preoperative analgesia. The standard protocol will be IV acetaminophen (Apotel) 1 g every 12 h and IV morphine sulfate 5 g as needed.
Category
Treatment - Devices

3

Description
Control group: Patients in the control group will only receive the standard protocol for preoperative analgesia without any additional intervention. The standard protocol will be IV acetaminophen (Apotel) 1 g every 12 h and IV morphine sulfate 5 g as needed.
Category
Treatment - Devices

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam Hossein hospital
Full name of responsible person
Farzad Amouzadeh Omrani
Street address
Tehran, Shahid Madani Avenue, Imam Hossein Hospital
City
Tehran
Province
Tehran
Postal code
1617763141
Phone
+98 21 7343 3000
Email
f.amouzadeh@sbmu.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Afshin Zarghi
Street address
7th Floor, Building Number 2, Shahid Beheshti University of Medical Sciences, Arabi Avenue, Daneshjoo Boulevard, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2712 2265
Email
Mpajouhesh@sbmu.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mohammad Ali Abdollahzadeh
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Orthopedics
Street address
Imam Hossein Hospital, Madani Ave, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1617763141
Phone
+98 21 7343 3000
Email
dr.mohammadali.abdollahzadeh@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Farzad Amouzadeh Omrani
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Orthopedics
Street address
Imam Hossein Hospital, Madani Ave, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1617763141
Phone
+98 21 7343 3000
Email
f.amouzadeh@sbmu.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Samin Khannejad
Position
Research associate
Latest degree
Medical doctor
Other areas of specialty/work
Orthopedics
Street address
Imam Hossein Hospital, Madani Ave, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1617763141
Phone
+98 21 7343 3000
Email
saminkhannejad@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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