Efficacy of acceptance and commitment therapy on electroencephalography, psychological flexibility, cognitive fusion, emotion regulation, symptom reduction, and oxytocin blood levels in people with obsessive-compulsive disorder

Determining the effectiveness of Acceptance and commitment therapy on changing the bandwidth of delta, beta 1, beta 2, theta beta coherence, changing the asymmetry of cognitive brain waves of the right hemisphere, cognitive flexibility, cognitive fusion, blood oxytocin level, regulation Excitement in people with obsessive-compulsive disorder

A clinical trial with a control group with a pre-test and post-test with three-month follow-up, single blind, randomly assigning patients to two groups using Excel software.

The statistical population includes individuals with OCD in Zanjan province. Patients who will be referred by psychiatrists and meet the inclusion criteria will be examined by the Structured Clinical Interview (SCID-I) and the Yale-Brown scale. Then, in a session before intervention, written consent will be obtained from patients, and demographic characteristics and other questionaairs will be filled. Oxytocin will be sampled subsequently.

Inclusion criteria: symptoms of OCD Comorbidity with other anxiety disorders 18-60 years no severe psychiatric disorders Not using drugs and alcohol in the last three months Not receiving psychological interventions not receive drug therapy in the last month written constent No chronic disease Exit criteria: Absence of more than two sessions Receive other psychological intervention simultaneously using drug at the same time no constent disorder aggreviation

Intervention group: Acceptance and commitment therapy will be individually during 8 sessions as Dr. Twohing's protocol by two therapists. The aim is mostly reducing anxiety and how to deal with obsessive thoughts and compulsions. Control group: will not receive any special therapy and only use evaluation sessions.

Brain waves, OCD symptoms, psychological flexibility

People who meet the entry criteria are referred by professors, counseling centers, and psychiatric clinics in Zanjan province and are randomly assigned to the experimental and control groups. Random allocation is done using Excel software. For this, in the first column, we enter 20 numbers 1 and 20 numbers 2 (representing the test and control group, respectively). Then, in the second column, we generate 46 random numbers using the (RAND) function. We sort the data based on column values containing random numbers (ascending or descending). With this sorting, the order of placement of numbers 1 and 2 will also change and be placed randomly. Based on the order of appearance of numbers 1 and 2, the samples are assigned to two groups.

Data will be made available to the journal and researchers only if needed, after de-identifying individuals.

Researchers start accessing documents and data files after 6 months to a year after the publication of the article.

Only the researchers and reviewers of the journal to which the article is submitted.

The data will be sent for review studies, where all analyzes must be supervised by one of the authors of the proposal.

After publishing the article, researchers can email the responsible author at elnaz48.mousavi@gmail.com to access the data. Or, if you wish, go to Shahid Beheshti Hospital to meet with Dr. Mousavi.

If the reason is scientific and the email is sent after the publication of the article, the requested information will be sent to them at least one week after consultation with other authors.