Comparison of bacterial nanocellulose wound dressings and standard treatment in the healing of second degree burn wounds: a randomized controlled clinical trial

Comparison of the use of nanocellulose dressing with the standard method of burn treatment in the recovery of patients with 2nd degree burns.

Controlled clinical trial with parallel groups, without blinding, randomized, phase 3 on 24 patients. Lottery of sealed envelopes will be used for randomization.

This trial will be conducted as a single center in the Shahid Madani accident center of Karaj. The number of 24 patients who meet the necessary conditions to participate in the study will be included in the study and randomly and by lottery will be placed in one of the groups of standard treatment or treatment with nanocellulose dressing. Duration of hospitalization, wound healing time, wound infection, hypertrophic scar and patient satisfaction with the treatment will be measured. The level of pain and itching of the patient on the first to third day will also be checked using VAS and finally all these items will be compared between the study groups.

Having second-degree burns in the limbs or trunk (with TBSA below 10%), being 18 and 75 years old, as well as not having chronic heart, vascular, liver and kidney diseases، not being pregnant, absence of infection in the burn wound and not being under treatment with systemic cortisone

The nanocellulose coating is placed on the wound and covered with a sterile gauze. In this group, the dressing will be changed every three days without removing the nanocellulose dressing.

Duration of hospitalization, wound healing time, wound infection, hypertrophic scar and patient satisfaction, the level of pain and itching of the patient on the first to third day

Sealed envelopes are considered as the number of patients, whose content determines which group each person belongs to. One of these envelopes is selected for each patient by lottery, and then this envelope is opened and the allocation of the patient will be determined after opening the envelopes.

All of the participants' individual data

Access starts 6 months after results are published

All researchers working in academic and scientific institutions and people working in the industry

If a request with this theme is received, a decision will be made with the opinion of the research team.

To the project manager, Dr. Hadi Pourjafar

After submitting the request to the project manager, this request will be reviewed by a committee with the presence of all the people involved in the project, and then if the committee gives a positive answer, the data will be provided to the applicant.