Investigating the effect of using atmospheric cold plasma radiation to heal wound healing in cutaneous leishmaniasis

Comparison of microbial culture, duration of wound closure, amount of wound exudate over time in the control group, and plasma in patients with salicylic ulcers.

In this study, blinding is done in a two-way blind way. The second phase of the clinical trial is on a group of 142 people, since the list of patients is not known in advance and the number of patients is not known. Every other day, plasma treatment or standard treatment is performed on the patients until A total of 71 subjects were obtained for each treatment. If 71 people are reached in the plasma or standard group, the treatment that has been completed is stopped.

one of the treatment groups, i.e. standard treatment alone or standard treatment together with plasma radiation treatment, and we conduct the study in a double-blind manner. Microbial culture will be done from the wounds of all participants at the beginning, the second week of treatment and the end of treatment, then the images will be analyzed with ImageJ software. Hospital of Damghan province

1- Age above 18 years. 2- Not having a history of radiation therapy. 3- Not taking chemotherapy drugs. 4- Not taking drugs that suppress the body's immune system. 5- Not having a severe infection that requires hospitalization. 6- Not having a severe bone infection (Osteomyelitis).

The standard treatment of Salk includes the injection of glucantim ampoules, and in the second group, i.e., the standard treatment with plasma radiation during 10 alternating sessions, in addition to the standard treatment, the patient's wound is swept with plasma radiation for 2 minutes.

Changes in the appearance and size of the wound after plasma processing؛ Reducing the rate of wound infection

The second phase of the clinical trial is on a group of 142 people since the list of patients is not known in advance and the number of patients is not known. A total of 71 subjects were obtained for each treatment. In case of reaching 71 people in the plasma or standard group, the treatment that has been completed is stopped and the only treatment that still needs patients (71 patients) is performed on people.

In the first group, plasma devices are used in the state where the gas flow is on and the patient will feel the gas flow, and in the second group, standard treatment with plasma radiation during 10 alternating sessions, the patient's wound with plasma radiation with a duration of 2 The minute is swept away. The condition of the wound is checked every week during the treatment, and when the wound is completely healed, the treatment is stopped, and the patient's condition will be followed up to one month later.

Publication of scientific research articles and ISI

The access period starts 6 months after the results are published

Researchers working in academic and scientific institutions

Checking the effectiveness of the treatment process

Dr. Mohammad Reza Khani, member of the faculty of Shahid Beheshti University, 09122531497

The request will be sent via email to m_khani@sbu.ac.ir and will be answered within 30 working days after review.