Comparison of repair of acute full-thickness defect wounds of the hand in repair with Alloderm compared to skin grafting

Comparison of repair with Eloderm and individual skin graft in terms of recovery time, cost, contouring and sensation

Phase two on two groups of 25 people will be randomly randomized, one will be repaired with autograft and the other will be repaired with allograft. The study is one-sided blind and only the patients do not know about the type of surgery and treatment selected. Also, this study will be conducted with parallel groups.

Performing reconstructive surgery for hand injuries in patients referred to Hazrat Fatemeh Hospital. The selection of the type of repair is explained based on the random selection and will be based on a lottery, in one group the repair will be done with allograft from cadaver and in the other group, the repair will be done with the person's own full-thickness autograft. In this study, only the participants did not know about the type of surgery, and the researcher and evaluator of the information were aware of the type of surgery, so the study is single-blind

Inclusion criteria: Complete skin damage of fingers and hand at volar or palmar level, People between 18 and 60 years old Exclusion criteria: People with a history of connective tissue disease and vascular collagen, People with a history of Steroid use, Smokers, Wounds with bone surfaces and open tendons

In one group, repair is done with hypotenar full thickness autograft, and in the intervention group, repair is done using Eloderm dressing along with split thickness autograft, which is a thin layer of epidermis

Evaluation of patients in terms of sensation, graft contouring, skin color, recovery time, treatment cost and duration of surgery

In this study, we numbered 50 papers in a container that cannot be seen from the outside and assigned number 1 to 25 papers and number 2 to the other 25, then before each patient's surgery in the operating room, we took out a paper from the container. And based on number 1 (repair with Eloderm) or 2 (repair with patient's skin graft), we determine the type of operation

This study is of a blind type, in which the patient is not aware of the study process and the placement of the study groups, but the researcher and evaluator of the information in the process of placement of people in the groups

The data file of the participants and the study protocol will be provided to the people after the study is done in the article and the final report of the thesis. Also, the informed consent form can be downloaded in the appendix of the thesis

One year after the end of the study

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