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Study aim
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Considering the prevalence of endometriosis and its debilitating symptoms and complications, which can affect the psychosocial parameters of a society by reducing the quality of life. By using drugs such as di-chiro-inositol, it is possible to help reduce the pain and complications of this disease by reducing the production of estrogen.
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Design
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Clinical trial with a control group, with parallel groups, double-blind, randomized, phase 2 on 100 patients. The rand function of Excel software was used for randomization.
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Settings and conduct
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Patients referring to Taleghani Hospital's gynaecology Clinic, receiving drug packages, patients and caregivers are blinded
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Participants/Inclusion and exclusion criteria
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Criteria for entering : age : between 20 and 40 years, refusal to receive other standard treatments pelvic pain that has been present for at least the last three months, diagnosis of endometriosis systemic estradiol higher than 90 pg/ml in the first 4 days after the end of the period, consent to start the plan and exclusion criteria from the plan: BMI>30), history of diabetes, history of tumors Secretion, use of hormones or inositol within 6 months before starting the study, use of other drugs, especially (OCP and...), any disease that interferes with the use of di chiro inositol, pregnancy/lactation
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Intervention groups
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In this RCT study, patients referring to the gynecology clinic, whose endometriosis has been confirmed using transvaginal ultrasound, will be determined and randomly divided into two equal groups. The goals and results obtained are discussed and an attempt is made to obtain the consent of the patients to participate in the study. A written consent is obtained from the patients who agree to participate. Then, the case and control groups are given separate medication packages.
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Main outcome variables
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dyspareunia; dysmenorrhea; pelvic pain; age; BMI; dyschezia