The Effect of Six Weeks of Exercise Snacking and Turmeric Supplement on Hepatic Enzymes of People with Non-Alcoholic Fatty Liver Disease

To identify the effect of six weeks of exercise snacking and turmeric supplement on hepatic enzymes and fatty liver grade of people with non alcoholic fatty liver disease

Clinical trial with control group, factorial design, single blinded, phase 3 on 40 patients. Randomization was done by an 8-sided dice.

After attending Dr. Samimi's office, participants will enter to the study, if they meet the requirements, and will be assigned to the either Exercise Snacking, Turmeric Supplement, Exercise Snacking and Turmeric Supplement, or Control group, randomly. They will be observed for six weeks and pretest and post test will be taken from them. This study is single blinded and the statistician and data analyst is not aware of the interventions.

The criteria for the study is being diagnosed with non alcoholic fatty liver disease and not having regular exercise and not taking turmeric supplement during a month prior to the starting date of the study.

Intervention Group 1: Exercise Snacking: High intensity short intervals of bodyweight exercise lasting about 5 minutes, three times a day, three days a week for 6 weeks. The exercises are as follows: First day: Jumping Jacks, High Knee Taps, Burpee. Second day: Air Squats, Push Ups, Skater Hops. Third day: Seal Jacks, Squat Kicks, Calf Raises. Intervention Group 2: Turmeric Supplement: One curcumin tablet (450 milligrams) daily to be taken with food, Produced by Dineh Inc, for 6 weeks. Intervention Group 3: Exercise Snacking and Turmeric Supplement for 6 weeks. Control Group: Without any interventions

Alkaline phosphatase; Aspartate transaminase; Alanine transaminase; Fatt liver grade

An 8-sided dice will be used for randomization. two numbers will be assigned to each groups and the dice will be rolled for each patient, and given the number on the dice, the participants will be in one of the four groups of Exercise Snacking, Turmeric Supplement, Exercise Snacking and Turmeric Supplement, and Control.

Blood test analysis and sonogram will be sent to the the statistician via office clerk. The results will be entered to SPSS and they will be labeled as 1, 2, 3, 4 for three intervention groups and one control group (that only the clerk will know of) and they will be analyzed by the statistician. Therefore, the statistician is not aware of the allocation of the interventions to the participants.