Comparison of frequency of Natural vaginal delivery after preparation of cervix with evening primrose, EASI mechanical method and misoprostol in 41 week pregnant women

Determining the frequency of normal delivery after using three groups of evening primrose, mechanical and misoprostol in 41-week pregnant women hospitalized in Fatemieh Hospital in 1401

A clinical trial of three groups, with parallel groups, randomized by random block allocation method, phase 3 on 420 pregnant women of 41 weeks.

Informed consent will be obtained from patients. After entering the delivery room, the patients undergo a vaginal examination and Bishop's score is calculated and then they are included in one of the three groups randomly. In the evening primrose group, one 1000 mg evening primrose capsule from Dana Pharmaceutical Company is prescribed vaginally every hour. Evening primrose is used until the beginning of the active phase of labor (exam 3-4 cm). In the mechanical group, using the Extra amnionic saline infusion method, a cervical Foley catheter is inserted and 30 cc of normal saline is injected per hour, and after inserting the balloon, the balloon is allowed to come out for a maximum of 12 hours. Then, in the third group of patients, misoprostol suppository 25 are placed vaginally. Bishop's score is determined every two hours in all three groups.

Inclusion criteria: Primiparous women at 41 weeks are candidates for termination of pregnancy by natural delivery Exclusion Criteria: Patients with active labor phase Patients with spontaneous onset of pain Not having an emergency delivery indication

The effect of three methods (evening flower, mechanical method and misoprostol) in the delivery process of primiparous pregnant mothers is investigated. Pregnant mothers are randomly divided into 3 groups.

Comparison of natural birth process, labor duration, side effects and condition of the baby in three groups of evening primrose, mechanical and misoprostol.

Patients will be consulted upon entering the hospital and informed consent will be obtained from the patient. After entering the delivery room, they undergo a vaginal examination and Bishop's score is calculated, and then they are included in one of the three groups randomly. Randomization is done by writing the letters A, B and C on three sheets and putting them in a box, and one of these sheets is taken out by the researcher for each patient. After completion, again for the next three patients, sheets will be removed with this random method until we reach the desired sample size.