Comparative evaluation of anesthetic efficacy of 1.8 milliliter Articaine and 3.6 milliliter of Articaine for infilteration anesthesia in mandibular canins with irreversible pulpitis: A randomized clinical

Determining the success rate of infiltration anesthesia injection of 1.8 milliliter Articaine and 3.6 milliliter Articaine in mandibular canins teeth with irreversible pulpitis

A clinical trial Consists of two intervention groups, with parallel groups, double-blind, randomized, on 84 patients, sealed envelopes will be used for randomization.

The study will be performed by 2 dentists in a private clinic in Rafsanjan. Before each injection, another dentist will randomly take out a piece of paper from the sealed envelope and according to the number, he will inject one of the two anesthetic volumes, so that in the first group, 1.8 milliliter of 4% Articaine solution (one anesthetic cartridge and three minutes later, the needle will be inserted into the anesthetic area without injection) and the second group, 3.6 milliliter of 4% Articaine solution (two anesthetic cartridges three minutes apart) so that the operator and the patient are not aware of the anesthesia volume. Patients are instructed to report any pain at any stage of Root canal treatment in Heft-Parker Visual Analog Scale form.

Inclusion criteria:Healthy adult patients 18–60 years old having mandibular canins tooth with symptomatic irreversible pulpitis. exclusion criteria:Spontaneous pain and patients who need emergency treatment.

In the 1st group, 1.8 milliliter of Articaine solution and in the second group, 3.6 milliliter of Articaine solution. 6 minutes after the anesthesia injection, the patient is asked about the numbness of the lower lip, and if the answer is negative, he is excluded the study, If the answer is positive, the tooth will be isolate by a rubberdam, the caries will be removed, the access cavity is prepared and instrumentation will be performed.

Pain rate by Visual Analogue Scale form

Simple randomizzation individually with using a sealed envelope The even and odd numbers from 1 to 84 (even numbers for injection of 2 cartridge articaine 4% and odd numbers for injection of 1 cartridge articaine 4%) are write on separate papers and placed in the one sealed envelope, and another dentist colleague randomly takes out a number from the envelope for each patient and performs an injection based on that.

Before each injection, another dentist will randomly take out a piece of paper and according to the number, he will inject one of the two anesthetic volumes, so that in the first group, 1.8 milliliter of 4% Articaine solution (one anesthetic cartridge and three minutes later, the needle will be inserted into the anesthetic area without injection) and the second group, 3.6 milliliter of 4% Articaine solution (two anesthetic cartridges three minutes apart) so that the operator and the patient are not aware of the anesthesia volume.

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