Comparison of the Effects of Single-Site and Dual-Site Transcranial Direct Current Stimulation on Exercise Performance and Psychophysiological Responses of Trained Men in an Endurance Exercise

Comparison the Effects of Single-Site and Dual-Site Transcranial Direct Current Stimulation on Exercise Performance and Psychophysiological Responses in an Endurance Exercise

In the present study, with within-subjects design, counterbalanced and double-blind design, 12 subjects will be randomly exposed to four different conditions.

This research will be done in Razi University. After selecting the subjects and familiarizing themselves with the research process, each subject will be exposed to four different conditions of electrical stimulation of the brain with a random combination. Then, the subjects will perform a time trial endurance activity. The principal investigator and subjects will not be aware of the type of stimulation received in each session.

Criteria for entering: Age range from 18 to 35 years. Endurance trained men with a history of at least one year of regular training. No color blindness or color vision disorders. being right-handed Criteria for not entering: Having any cardiovascular, pulmonary and metabolic disease. History of seizures, epilepsy or other types of neurological diseases. The presence of implantable devices or pacemakers in the body. Smoking and alcohol consumption.

This study is an intra-group and counterbalanced study in which the subjects are exposed to four different conditions of brain stimulation including: 1) anodal stimulation of the primary motor cortex, 2) anodal stimulation of the posterior-lateral prefrontal cortex, 3) two-zone anodal stimulation, 4) sham stimulation (placebo effect) will be placed. Also, the duration of brain stimulation will be 20 minutes and its intensity will be 2 milliamps.

change in endurance performance; the degree of perception of pressure; electromyography; cognitive function; reaction time

In this study, in order to randomize the order of subject exposure to four different conditions (4 different types of electrical stimulation of the brain), the Latin square method will be used. For this purpose, first, using the website www.random.org, each subject will be randomly assigned a number between 1 and 12 as an identification code. Then, the English letters D, C, B, A are assigned to four intervention conditions and a Latin square will be created with four rows and four columns. After creating the Latin square, participants number 1 to 3 in the sequence of the first row, participants 4 to 6 in the sequence of the second row, participants 7 to 9 in the sequence of the third row and participants 10 to 12 in the sequence of the fourth row will be placed.

In this double-blind study, the researcher and participants will be blinded to the type of transcranial electrical stimulation used and the location of stimulation in each session. In the present study, the Neurostim stimulation device was used to induce direct current electrical stimulation in four separate sessions and four different modes including: 1) anodal stimulation of the primary motor cortex, 2) anodal stimulation of the posterior-lateral prefrontal cortex, 3) anodal stimulation of the two regional, 4) sham stimulation (placebo) will be used. For this purpose, a person outside the research team will be responsible for applying electrical stimulation in four experimental sessions. In order to blind the participants, after they sit on a special chair, the electrical stimulation device of the brain is hidden from their sight and covered by a cover completely, and the electrodes will be placed on the desired areas by the examiner. In order to blind the researcher, before the intervention, the researcher leaves the laboratory and returns to the test site after the stimulation period has passed and the electrodes are removed and the stimulation device is turned off. Also, in the sham stimulation mode, according to standard protocols, the active current is induced on the head for 30 seconds to induce the same sensation as the active stimulation mode, and then the current is cut off and the stimulation is deactivated.

All data can be shared after de-identifying subjects.

6 months after printing the results

Researchers

For meta-analytic research

If you need to receive documents, send an email to Hasna Khoshchehre, research researcher, with the email address: h.khoshchehre98@gmail.com.

In case of an official request, stating the relevant reasons and mentioning the complete details, the data will be sent via email after 72 hours.