Investigating the effect of 2% chlorhexidine gel inside the socket on pain after surgery of the third molar of the mandible.

Investigating the effect of 2% chlorhexidine gel internally on pain after mandibular impacted third molar surgery

Clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 17 patients, each patient has 2 samples. Randomization using the Excel Randbetween function option

This study is conducted in the Faculty of Dentistry of Tehran Azad University in the Department of Oral and Maxillofacial Surgery. researcher and the patient are blinded to the study but clinician is blind. After anesthetic injection, a mucoperiosteal flap will be applied and the tooth will be loosened and removed with an elevator. Chlorhexidine 2% gel will be placed on the tested side, which is randomly selected, along with gelfoam, and gelfoam will be placed on the control side after surgery, then sutures will be applied. It is simple. All patients are given the usual care after surgery (such as painkillers). Demographic data of patients including age, gender, amount of pain while taking painkillers and the number of painkillers used are recorded. The pain level after surgery is evaluated by VAS criteria. Evaluations are performed on both the first and third days after the operation (2, 12, 24, 72 hours after the operation,).

People who are fully satisfied after explaining the procedures and purpose of the research and do not have any specific systemic problems and are 18-25 years old and need bilateral lower third molar surgery.

Intervention group: Placing 2% chlorhexidine gel in the socket of one side (right or left) of the impacted impacted third molar, control group: Placing placebo on the other side.

Pain at 2,12,24,72 hours after surgery on the intervention and control side based on VAS criteria.The VAS is a score from 1-10 , (1: no pain,10: unbearable pain).

In each patient, in a simple random manner (by Excel software using the Randbetween function option), the impacted molar tooth on one side is considered as the case group and the other side as the control.

Before starting the surgery, the research procedures were explained to the patient, and a consent form was obtained from him or her. On the day of the surgery, the resident (clinician who is not blinded to the study) at Tehran Azad Dental School after surgery and tooth extraction on the Intervention side, which is chosen by simple random before the surgery, he puts chlorhexidine gel and placebo on the control side and writes the information in a form and puts it in a closed envelope and hands it to the researcher. The patient and the researcher, who is the outcome evaluator, are blind, and after evaluating the outcome (which is the evaluation of the patient's pain in each side), he opens the information form and compares and analyzes the data.

The research process and the main results of the research and data about the patients are accessible

1 year after the results are published

Researchers working in academic and scientific institutions and people working in industry can apply for them

If the patient is fully satisfied and if it is aimed at improving the patient's condition and preventing the patient's problems, the documents can be used and available

You can contact this email for correspondence and exchange of views arya.fathi77.af@gmail.com

It must be for research or treatment