The effect of acute oral ketone supplementation on the response of some appetite-related peptides to one-bout of sprint intermittent exercise in overweight men

Investigating the effect of acute oral ketone supplementation on the response of some appetite-related peptides to one-bout of sprint intermittent exercise in overweight men

This research will be conducted as a randomized, crossover, double-blind clinical trial on two groups, each consisting of 8 participants.

After recruiting volunteers at the university, they will be asked to provide personal information (age, height, weight, and daily physical activity) and participate in a session where the research objectives and methodology will be explained to them. After completing the consent forms, initial measurements (body composition, maximum aerobic capacity, anaerobic power, and maximal fat oxidation) will take place. Then, 16 participants will be randomly selected and assigned to two homogeneous groups (group one: placebo plus exercise, group two: ketone salt supplementation plus exercise). blood samples will be collected before and after consumption.

Inclusion criteria: Being a male Being 18 to 35 years old Having BMI between 25 to 30 exclusion criteria: Having a history of any kind of injury Being a regular smoker Diagnosed with chronic diseases Followed a ketogenic diet in the past six months

Intervention group: The intervention involves consuming a single serving of ketone salt (KETO CaNa), a dietary supplement produced by KETO SPORTS in the United States. Each serving weighs 19 grams and contains 11.7 grams of beta-hydroxybutyrate, 1.1 grams of calcium, 1.3 grams of sodium, and 55 calories. It will be provided to the participants as a solution dissolved in 300 milliliters of water. Control group: The control group will consume an isocaloric and isovolume placebo consisting of oral glucose and flavoring, dissolved in 300 milliliters of water.

The appetite rate

After initial evaluations, participants will be randomly allocated into two homogeneous groups (Groups A and B) based on body mass index, maximum oxygen consumption, and aerobic power (Wingate). This randomization process will be carried out using IBM SPSS statistical software through simple randomization. The allocation will be done individually by a third party, ensuring that each participant is assigned to either Group A or Group B to prevent bias in group assignments.

Using edible flavorings, food supplement beverages, or glucose placebo beverages, identical in terms of volume, calories, taste, and smell, will be prepared by a third party. These solutions will be dissolved in three hundred milliliters of water and provided to the participants in identical opaque cups. Both the participants and the researchers responsible for data collection and evaluation will not know the order of consumption of the food supplement beverage or glucose placebo beverage.

All data obtained from this study will be statistically analyzed, and relevant conclusions will be drawn to form a research article. After undergoing peer review, the article will be published in a scientific journal. The personal information and details of the participants will not be disclosed in accordance with ethical principles.

after the results are published in a scientific article, the study data will be accessible. This means that the collected data, along with the corresponding results and conclusions, will be made available for reference and utilization by other researchers and interested individuals.

Those who have permission to access data and documents include participants in the study, members of the research team, interested persons, and relevant officials. Of course, access to data must be done in compliance with ethical principles, privacy, and relevant laws.

Data and documentation will be used to provide scientific information and evidence for further research, and statistical analysis, confirm or reject hypotheses, develop new theories, evaluate and analyze previous results, and support related decisions in various fields.

The data will be readily accessible by simply visiting the website of the scientific journal publishing the research article.

The data will be readily accessible by simply visiting the website of the scientific journal publishing the research article.