Evaluation of the Effect of Topical use of Chamomile oil and Dill oil on Abdominal Obesity and Comparison with Placebo Group_ A Randomized Clinical Trial

Determining the effect of topical application of chamomile and dill oil on abdominal obesity

Randomized clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 60 patients, rand function of Excel software was used for randomization.

This study is conducted in the form of a double-blind randomized clinical trial among those who refer to Iranian medical treatment centers.

Main Inclusion Criteria: Women between the ages of 25 and 55 years with a waist circumference of >= 80 cm who have the necessary cooperation in taking the medicine and are not pregnant. Main Exclusion Criteria: Not using another topical drug that interferes with the effect of the studied drug Use other weight loss methods

Intervention group: 6 weeks of the combination of chamomile oil and dill oil once a day in the amount of 2 cc per square meter (in such a way that the entire abdominal area except for the radius of 2 cm around the navel (10 cm square) is completely lubricated and with a thin layer of oil should be covered) without massaging the area. After using the oil, cover the area with a plastic cover and have 30 minutes of aerobic activity and the plastic cover is removed from the abdomen after the aerobic activity. Control group: topical use of placebo oil (sesame oil) according to the instructions of the intervention group

1- Abdominal circumference size 2- Abdominal subcutaneous fat thickness in three areas

Patients are divided into case and control groups by random allocation method. block randomization method and table of random numbers are used to prepare the random list. It is taken in the way that we design a random block with 6 rows and 10 columns and write down the number of 30 letters A and 30 letters B randomly in its houses. With the first patient's visit, the first cell from row 1 of column 1 is selected and assigned to the intervention or control group based on the letter in the patient's cell, and then we draw a line on the corresponding letter with the selected meaning. We do the same for the rest of the patients to finally reach the determined sample size. We made 60 cards and write letter A on 30 for intervention and on the other 30 letter B for the control group. Then put them inside the envelope with aluminum wrap and put in a box. At the time of patient arrival, one of the envelopes randomly will be selected and open it, based on selected letter (A or B) patients will be assigned to intervention or control group.

The intervention group will receive a can of chamomile and dill oil, and the placebo group will receive a can of sesame oil. The medicine of both groups is ready to be delivered in similar packaging and in a can with dull color. The lid of the placebo oil can is smeared with chamomile and dill essential oil.