Investigating the effect of Melissa officinalis capsule on the sexual function of Menopause women

Determining the effect of Melissa capsules on sexual function of postmenopausal women

A clinical trial with a control group. with parallel groups, triple blind, randomized, phase 3 on 100 patients. Excel software is used for randomization.

The researcher selects four centers from the comprehensive health service centers affiliated to SBMU located in the north and east of Tehran by simple random sampling, then eligible postmenopausal women are attended. The informed consent form and relevant questionnaires are completed. Women are randomly assigned to groups 1 or 2 using Excel software in the same order as they enter the study and each group is given a medicine. The researcher, the samples, and the statistical consultant are unaware of what medicine each envelope contains except for pharmaceutical consultant. After the completion of the two-month period, the FSFI questionnaire is completed again because it measures sexual function in the previous month, it is completed again one month after the end of the course. Finally, the data is analyzed by a statistical consultant.

in Iranian cases, at least one year had passed since their menses, do not has hormone replacement therapy, has sexual activity, menopausal women and their husband known for no mental illness, no addiction to smoking or drugs, not acquire depression and anxiety, unknown for any chronic diseases, is not allergenic to medicinal plants and gluten, If cases show sensitivity to Melissa capsules, has not used capsules for two days or more, hasn't taken regularly and the person is reluctant to continue the treatment are removed.

In intervention group, the samples consumed one Melissa capsule daily, and in the control group, the capsule containing dry bread was consumed for two months.

Sexual function score.

First, in order to select health service centers, the researcher needs to select four centers by simple random sampling. Random numbers function of Excel software is used to randomize the samples into intervention and control groups. to this extent, the numbers represented the samples are sorted from 1 to 100 then written in order in the first column and in the next column, the numbers 1 and 2 are randomly placed in front of each sample. Finally, the samples are divided into two groups in the same order as they enter the study.

This study is a triple-blind randomized clinical study. Therefore, the researcher, the research units, and the statistics consultant professor are not aware of the coding and what sort of medicine each package contains and only the pharmaceutical consultant of the research is aware of the coding of the envelopes and the type of drugs.