The effect of eight weeks of selenium supplementation and Concurrent training on SOD, CAT, CRP, GPX, GR and lipid profile in elderly men

The purpose of this study is to investigate the effect of eight weeks of selenium supplementation with concurrent training on SOD CAT, CRP, GPX and lipid profiles of elderly men.

A clinical trial with a pre-test-post-test semi-experimental design with a control group, double-blind, phase 4 on 48 elderly men using the PASS 2023 software (NCSS, LLC, Kaysville, Utah, USA, ncss.com/software/pass ) the subjects will be divided into 6 parallel groups of 8 people and will be placed in one of the following groups: supplement, placebo, control, concurent training, concurent training+supplement, concurent training+placebo. The supplement groups will receive 200 micrograms of Selenium supplement with the American brand Naturemid. Maltodextrin will also be used as a placebo and in completely similar capsules as a placebo. The training program will be done 3 days a week on non-consecutive days for 8 weeks, each session will be 60 minutes in the morning.

This study will be conducted in Kahrizak home of Alborz province on the elderly in a double blind method (subjects, researchers and executive staff and data analyzers are not aware of the contents of the capsules until the end of extracting the results).

The criteria for inclusion in the study are elderly men with the age of at least 65 and at most 75 years, the ability to perform physical and daily activities, the absence of underlying diseases such as diabetes, cardiovascular disease, and skeletal and joint abnormalities.

After selecting the subjects, 48 elderly men will be divided into 6 groups of 8 people: supplement, placebo, control, concurent training, concurent training group+supplement, concurent training+placebo.

Improving the condition of the elderly using a combination of supplements and exercise

After finalizing the 48 subjects and assigning codes 1 to 48 to each subject individually and using the PASS 2023 software (NCSS, LLC, Kaysville, Utah, USA, ncss.com/software/pass), the subjects were will be randomly divided into 6 groups of 8 people.

This research will be done in a double blind way. After explaining the conditions and how to conduct the research to the subjects, they will be divided into six groups. Supplemental group, placebo group, control group, concurrent training group, concurrent training+supplement group, concurrent training+placebo group. None of the participants, the executive staff of nurses, physiotherapists, etc., practitioners and students (researcher) will know about the contents of the capsules. Which group will use the supplement and which group will use the placebo, the subjects and the researcher will not know. And this work will be determined by a third party as a reference person. In this way, the capsules containing placebo and supplement will be coded and provided by the researcher to the specified groups. At the end of the research and after collecting the blood sample and measuring the dependent variables, the data will be collected and provided to the supervisor, and after the data analysis and the results are determined, the codes will be opened and the supplement and placebo groups will be determined.

The results of the main outcomes will be published as articles in journals.

6 months after the results are published

Researchers working in academic institutions

For use in review articles and meta-analysis

Rouhollah Haghshenas, Email: rhm@semnan.ac.ir

One week after the applicant's request and necessary checks, the necessary information will be sent via email.